UniProt P0A9G4
HTH-type transcriptional regulator CueR (P0A9G4)
HTH-type transcriptional regulator CueR (UniProt P0A9G4): 18 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0A9G4
- Protein
- HTH-type transcriptional regulator CueR
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 8 · 2 records with a druggable one
Structures
19 records of P0A9G4 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1Q05 | Crystal structure of the Cu(I) form of E. coli CueR, a copper efflux regulator | x-ray diffraction | A, B | CU1 | — |
| 1Q05 | Crystal structure of the CU(I) form of E. COLI cuer, a copper efflux regulator | x-ray diffraction | A, B | — | — |
| 1Q06 | Crystal structure of the Ag(I) form of E. coli CueR, a copper efflux regulator | x-ray diffraction | A, B | AG | — |
| 1Q06 | Crystal structure of the AG(I) form of E. COLI cuer, a copper efflux regulator | x-ray diffraction | A, B | — | — |
| 1Q07 | Crystal structure of the Au(I) form of E. coli CueR, a copper efflux regulator | x-ray diffraction | A, B | AU | — |
| 1Q07 | Crystal structure of the AU(I) form of E. COLI cuer, a copper efflux regulator | x-ray diffraction | A, B | — | — |
| 4WLS | Crystal structure of the metal-free (repressor) form of E. Coli CUER, a copper efflux regulator… | x-ray diffraction | A, B | — | 4 (best 0.59) |
| 4WLS | Crystal structure of the metal-free (repressor) form of E. COLI cuer, a copper efflux regulator… | x-ray diffraction | A, B | — | — |
| 4WLW | Crystal structure of the AG(I) (activator) form of E. COLI cuer, a copper efflux regulator, bound… | x-ray diffraction | A | — | — |
| 4WLW | Crystal structure of the AG(I) (activator) form of E. COLI cuer, a copper efflux regulator, bound… | x-ray diffraction | A | — | — |
| 6LDI | The cryo-EM structure of E. coli CueR transcription activation complex | electron microscopy | G, H | AG | — |
| 6LDI | The cryo-EM structure of E. COLI cuer transcription activation complex | electron microscopy | G, H | AG | — |
| 6XH7 | CueR-TAC without RNA | electron microscopy | G, H | CU | — |
| 6XH7 | Cuer-tac without RNA | electron microscopy | G, H | CU | — |
| 6XH8 | CueR-transcription activation complex with RNA transcript | electron microscopy | G, H | CU | — |
| 6XH8 | Cuer-transcription activation complex with RNA transcript | electron microscopy | G, H | CU | — |
| 7C17 | The cryo-EM structure of E. coli CueR transcription activation complex with fully duplex promoter… | electron microscopy | G, H | AG | 4 (best 0.75) |
| 7C17 | The cryo-EM structure of E. COLI cuer transcription activation complex with fully duplex promoter… | electron microscopy | G, H | AG | — |
| P0A9G4 | AlphaFold monomer V2.0 prediction for hth-type transcriptional regulator cuer (P0A9G4) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1Q06 chain B against the predicted model P0A9G4: TM-score 0.96, RMSD 0.83 Å
- 1Q06 chain B against the predicted model P0A9G4: TM-score 0.96, RMSD 0.83 Å
- 1Q07 chain B against the predicted model P0A9G4: TM-score 0.96, RMSD 0.83 Å
- 1Q07 chain B against the predicted model P0A9G4: TM-score 0.96, RMSD 0.83 Å
- 1Q05 chain B against the predicted model P0A9G4: TM-score 0.96, RMSD 0.85 Å
- 1Q05 chain B against the predicted model P0A9G4: TM-score 0.96, RMSD 0.85 Å
- 4WLW chain A against the predicted model P0A9G4: TM-score 0.96, RMSD 0.89 Å
- 4WLW chain A against the predicted model P0A9G4: TM-score 0.96, RMSD 0.89 Å
- 6XH7 chain H against the predicted model P0A9G4: TM-score 0.94, RMSD 1.08 Å
- 6XH7 chain H against the predicted model P0A9G4: TM-score 0.94, RMSD 1.08 Å
Elsewhere
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