UniProt P0A850
Trigger factor (P0A850)
Trigger factor (UniProt P0A850), EC 5.2.1.8: 15 experimental structures and 1 predicted model on GenesisL1, 36 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0A850
- Protein
- Trigger factor
- EC
- 5.2.1.8
- Experimental structures
- 15
- Predicted models
- 1
- Pockets
- 36 · 2 records with a druggable one
Structures
16 records of P0A850 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1L1P | Solution Structure of the PPIase Domain from E. coli Trigger Factor | solution nmr | A | — | — |
| 1L1P | Solution structure of the ppiase domain from E. COLI trigger factor | solution nmr | A | — | — |
| 1OMS | Structure determination by MAD: E.coli Trigger Factor binding at the ribosomal exit tunnel. | x-ray diffraction | A, B, C | — | — |
| 1OMS | Structure determination by mad: E.COLI trigger factor binding at the ribosomal exit tunnel. | x-ray diffraction | A, B, C | — | — |
| 1P9Y | Ribosome binding of E. coli Trigger Factor mutant F44L. | x-ray diffraction | A, B | — | — |
| 1P9Y | Ribosome binding of E. COLI trigger factor mutant F44L. | x-ray diffraction | A, B | — | — |
| 2VRH | Structure of the E. coli trigger factor bound to a translating ribosome | electron microscopy | A | — | — |
| 2VRH | Structure of the E. COLI trigger factor bound to a translating ribosome | electron microscopy | A | — | — |
| 5OWI | The dynamic dimer structure of the chaperone Trigger Factor (conformer 1) | solution nmr | A, B | — | 17 (best 0.81) |
| 5OWI | The dynamic dimer structure of the chaperone trigger factor (conformer 1) | solution nmr | A, B | — | — |
| 5OWJ | The dynamic dimer structure of the chaperone Trigger Factor (conformer 2) | solution nmr | A, B | — | 18 (best 0.73) |
| 5OWJ | The dynamic dimer structure of the chaperone trigger factor (conformer 2) | solution nmr | A, B | — | — |
| 6D6S | Solution structure of trigger factor dimer | solution nmr | A, B | — | — |
| 7D6Z | Molecular model of the cryo-EM structure of 70S ribosome in complex with peptide deformylase and… | electron microscopy | h | — | — |
| 7D80 | Molecular model of the cryo-EM structure of 70S ribosome in complex with peptide deformylase… | electron microscopy | 5 | — | — |
| P0A850 | AlphaFold monomer V2.0 prediction for trigger factor (P0A850) | predicted | A | — | 1 (best 0.41) |
Experiment against prediction
- 1OMS chain B against the predicted model P0A850: TM-score 0.97, RMSD 0.72 Å
- 1OMS chain B against the predicted model P0A850: TM-score 0.97, RMSD 0.72 Å
- 1OMS chain C against the predicted model P0A850: TM-score 0.94, RMSD 1.12 Å
- 1OMS chain C against the predicted model P0A850: TM-score 0.94, RMSD 1.12 Å
- 1OMS chain A against the predicted model P0A850: TM-score 0.92, RMSD 1.61 Å
- 1OMS chain A against the predicted model P0A850: TM-score 0.92, RMSD 1.61 Å
- 1P9Y chain A against the predicted model P0A850: TM-score 0.91, RMSD 1.58 Å
- 1P9Y chain A against the predicted model P0A850: TM-score 0.91, RMSD 1.58 Å
- 2VRH chain A against the predicted model P0A850: TM-score 0.86, RMSD 3.16 Å
- 2VRH chain A against the predicted model P0A850: TM-score 0.86, RMSD 3.16 Å
Elsewhere
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