UniProt P0A7T7
30S ribosomal protein S18 (P0A7T7)
30S ribosomal protein S18 (UniProt P0A7T7): 317 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 49 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0A7T7
- Protein
- 30S ribosomal protein S18
- Experimental structures
- 317
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 49 · 34 records with a druggable one
Structures
318 records of P0A7T7 in the MolNFT archive: 317 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3J9Y | Cryo-EM structure of tetracycline resistance protein TetM bound to a translating E.coli ribosome | electron microscopy | r | — | — |
| 3J9Z | Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G | electron microscopy | SR | — | — |
| 3JA1 | Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G | electron microscopy | SR | — | — |
| 3JBU | Mechanisms of Ribosome Stalling by SecM at Multiple Elongation Steps | electron microscopy | R | — | — |
| 3JBV | Mechanisms of Ribosome Stalling by SecM at Multiple Elongation Steps | electron microscopy | R | — | — |
| 3JCD | Structure of Escherichia coli EF4 in posttranslocational ribosomes (Post EF4) | electron microscopy | r | — | — |
| 3JCE | Structure of Escherichia coli EF4 in pretranslocational ribosomes (Pre EF4) | electron microscopy | r | — | — |
| 3JCJ | Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association | electron microscopy | 1 | — | — |
| 3JCN | Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association… | electron microscopy | u | — | — |
| 4A2I | Cryo-electron Microscopy Structure of the 30S Subunit in Complex with the YjeQ Biogenesis Factor | electron microscopy | R | — | — |
| 4A2I | Cryo-electron microscopy structure of the 30S subunit in complex with the yjeq biogenesis factor | electron microscopy | R | — | — |
| 4ADV | Structure of the E. coli methyltransferase KsgA bound to the E. coli 30S ribosomal subunit | electron microscopy | R | — | — |
| 4ADV | Structure of the E. COLI methyltransferase ksga bound to the E. COLI 30S ribosomal subunit | electron microscopy | R | — | — |
| 4U1U | Crystal structure of the E. coli ribosome bound to quinupristin. | x-ray diffraction | AR, CR | — | — |
| 4U1V | Crystal structure of the E. coli ribosome bound to linopristin. | x-ray diffraction | AR, CR | — | — |
| 4U20 | Crystal structure of the E. coli ribosome bound to flopristin. | x-ray diffraction | AR, CR | — | — |
| 4U24 | Crystal structure of the E. coli ribosome bound to dalfopristin. | x-ray diffraction | AR, CR | — | — |
| 4U25 | Crystal structure of the E. coli ribosome bound to virginiamycin M1. | x-ray diffraction | AR, CR | — | — |
| 4U26 | Crystal structure of the E. coli ribosome bound to dalfopristin and quinupristin. | x-ray diffraction | AR, CR | — | — |
| 4U27 | Crystal structure of the E. coli ribosome bound to flopristin and linopristin. | x-ray diffraction | AR, CR | — | — |
| 4V47 | Real space refined coordinates of the 30S and 50S subunits fitted into the low resolution cryo-EM… | electron microscopy | BR | — | — |
| 4V4H | Crystal structure of the bacterial ribosome from Escherichia coli in complex with the antibiotic… | x-ray diffraction | AR, CR | — | — |
| 4V4Q | Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution. | x-ray diffraction | AR, CR | — | — |
| 4V4V | Structure of a pre-translocational E. coli ribosome obtained by fitting atomic models for RNA and… | electron microscopy | AR | — | — |
| 4V4W | Structure of a SecM-stalled E. coli ribosome complex obtained by fitting atomic models for RNA and… | electron microscopy | AR | — | — |
| 4V50 | Crystal Structure of Ribosome with messenger RNA and the Anticodon stem-loop of P-site tRNA. | x-ray diffraction | AR, CR | — | — |
| 4V52 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with neomycin. | x-ray diffraction | AR, CR | — | — |
| 4V53 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with gentamicin. | x-ray diffraction | AR, CR | — | — |
| 4V54 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with ribosome… | x-ray diffraction | AR, CR | — | — |
| 4V55 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with gentamicin and… | x-ray diffraction | AR, CR | — | — |
| 4V56 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin. | x-ray diffraction | AR, CR | — | — |
| 4V57 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin and… | x-ray diffraction | AR, CR | — | — |
| 4V5B | Structure of PDF binding helix in complex with the ribosome. | x-ray diffraction | BR | — | — |
| 4V5H | E.Coli 70s Ribosome Stalled During Translation Of Tnac Leader Peptide. | electron microscopy | AR | — | — |
| 4V5Y | Crystal structure of the bacterial ribosome from Escherichia coli in complex with paromomycin and… | x-ray diffraction | AR, CR | — | — |
| 4V64 | Crystal structure of the bacterial ribosome from Escherichia coli in complex with hygromycin B. | x-ray diffraction | AR, CR | — | — |
| 4V65 | Structure of the E. coli ribosome in the Pre-accommodation state | electron microscopy | AK | — | — |
| 4V66 | Structure of the E. coli ribosome and the tRNAs in Post-accommodation state | electron microscopy | AK | — | — |
| 4V69 | Ternary complex-bound E.coli 70S ribosome. | electron microscopy | AR | — | — |
| 4V6C | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | x-ray diffraction | AR, CR | — | — |
| 4V6D | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | x-ray diffraction | AR, CR | — | — |
| 4V6E | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | x-ray diffraction | AR, CR | — | — |
| 4V6K | Structural insights into cognate vs. near-cognate discrimination during decoding. | electron microscopy | BV | — | — |
| 4V6L | Structural insights into cognate vs. near-cognate discrimination during decoding. | electron microscopy | AV | — | — |
| 4V6M | Structure of the ribosome-SecYE complex in the membrane environment | electron microscopy | AR | — | — |
| 4V6N | Structural characterization of mRNA-tRNA translocation intermediates (50S ribosome of class2 of the… | electron microscopy | BU | — | — |
| 4V6O | Structural characterization of mRNA-tRNA translocation intermediates (class 4a of the six classes) | electron microscopy | AU | — | — |
| 4V6P | Structural characterization of mRNA-tRNA translocation intermediates (class 4b of the six classes) | electron microscopy | AU | — | — |
| 4V6Q | Structural characterization of mRNA-tRNA translocation intermediates (class 5 of the six classes) | electron microscopy | AU | — | — |
| 4V6R | Structural characterization of mRNA-tRNA translocation intermediates (class 6 of the six classes) | electron microscopy | AU | — | — |
| 4V6S | Structural characterization of mRNA-tRNA translocation intermediates (class 3 of the six classes) | electron microscopy | BT | — | — |
| 4V6T | Structure of the bacterial ribosome complexed by tmRNA-SmpB and EF-G during translocation and… | electron microscopy | AR | — | — |
| 4V6Y | E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in classic pre-translocation state (pre1a) | electron microscopy | AR | — | — |
| 4V6Z | E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in classic pre-translocation state (pre1b) | electron microscopy | AR | — | — |
| 4V70 | E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in intermediate pre-translocation state (pre3) | electron microscopy | AR | — | — |
| 4V71 | E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in intermediate pre-translocation state (pre2) | electron microscopy | AR | — | — |
| 4V72 | E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in hybrid pre-translocation state (pre4) | electron microscopy | AR | — | — |
| 4V73 | E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in hybrid pre-translocation state (pre5a) | electron microscopy | AR | — | — |
| 4V74 | 70S-fMetVal-tRNAVal-tRNAfMet complex in hybrid pre-translocation state (pre5b) | electron microscopy | AR | — | — |
| 4V75 | E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in classic post-translocation state (post1) | electron microscopy | AR | — | — |
258 records more on the page itself.
Ligands
- MG · Magnesium ion · in 3 records
- 84D · Dibekacin · in 1 record
- AM2 · Apramycin · in 1 record
- LLL · (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-diamino-3-((2R, 3R,6S)-3-amino-6-(aminomethyl)-tetrahydro-2H-pyran-2-yloxy)-2-hydroxycyclohexyloxy)-5-methyl-4-(methylamino)-tetrahydro-2H-pyran-3,5-diol · in 1 record
Experiment against prediction
- 5JC9 chain AR against the predicted model P0A7T7: TM-score 0.97, RMSD 0.43 Å
- 5J5B chain AR against the predicted model P0A7T7: TM-score 0.97, RMSD 0.47 Å
- 5J7L chain AR against the predicted model P0A7T7: TM-score 0.97, RMSD 0.47 Å
- 5IT8 chain AR against the predicted model P0A7T7: TM-score 0.97, RMSD 0.49 Å
- 4YBB chain AR against the predicted model P0A7T7: TM-score 0.97, RMSD 0.50 Å
- 9GUT chain S against the predicted model P0A7T7: TM-score 0.96, RMSD 0.61 Å
- 5MDW chain w against the predicted model P0A7T7: TM-score 0.96, RMSD 0.62 Å
- 9GUP chain S against the predicted model P0A7T7: TM-score 0.96, RMSD 0.65 Å
- 4V9O chain BR against the predicted model P0A7T7: TM-score 0.96, RMSD 0.93 Å
- 4V7B chain AR against the predicted model P0A7T7: TM-score 0.96, RMSD 0.93 Å
Elsewhere
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