UniProt P0A7M9
50S ribosomal protein L31 (P0A7M9)
50S ribosomal protein L31 (UniProt P0A7M9): 71 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0A7M9
- Protein
- 50S ribosomal protein L31
- Experimental structures
- 71
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 11 · 11 records with a druggable one
Structures
72 records of P0A7M9 in the MolNFT archive: 71 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2J28 | Model of E. COLI srp bound to 70S rncs | electron microscopy | Z | — | — |
| 2J28 | Model of E. COLI srp bound to 70S rncs | electron microscopy | Z | — | — |
| 2RDO | 50S subunit with EF-G(GDPNP) and RRF bound | electron microscopy | Z | — | — |
| 2RDO | 50S subunit with ef-G(GDPNP) and rrf bound | electron microscopy | Z | — | — |
| 3BBX | The Hsp15 protein fitted into the low resolution Cryo-EM map of the 50S.nc-tRNA.Hsp15 complex | electron microscopy | Z | — | — |
| 3BBX | The HSP15 protein fitted into the low resolution cryo-EM MAP of the 50S.NC-TRNA.HSP15 complex | electron microscopy | Z | — | — |
| 3J9Y | Cryo-EM structure of tetracycline resistance protein TetM bound to a translating E.coli ribosome | electron microscopy | 6 | — | — |
| 3J9Z | Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G | electron microscopy | LZ | — | — |
| 3JA1 | Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G | electron microscopy | L2 | — | — |
| 4V4H | Crystal structure of the bacterial ribosome from Escherichia coli in complex with the antibiotic… | x-ray diffraction | BZ, DZ | — | — |
| 4V4Q | Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution. | x-ray diffraction | BZ, DZ | — | — |
| 4V65 | Structure of the E. coli ribosome in the Pre-accommodation state | electron microscopy | BS | — | — |
| 4V66 | Structure of the E. coli ribosome and the tRNAs in Post-accommodation state | electron microscopy | BS | — | — |
| 4V6K | Structural insights into cognate vs. near-cognate discrimination during decoding. | electron microscopy | Ab | — | — |
| 4V6L | Structural insights into cognate vs. near-cognate discrimination during decoding. | electron microscopy | Bb | — | — |
| 4V6N | Structural characterization of mRNA-tRNA translocation intermediates (50S ribosome of class2 of the… | electron microscopy | A2 | — | — |
| 4V6O | Structural characterization of mRNA-tRNA translocation intermediates (class 4a of the six classes) | electron microscopy | B2 | — | — |
| 4V6P | Structural characterization of mRNA-tRNA translocation intermediates (class 4b of the six classes) | electron microscopy | B2 | — | — |
| 4V6Q | Structural characterization of mRNA-tRNA translocation intermediates (class 5 of the six classes) | electron microscopy | B2 | — | — |
| 4V6R | Structural characterization of mRNA-tRNA translocation intermediates (class 6 of the six classes) | electron microscopy | B2 | — | — |
| 4V6S | Structural characterization of mRNA-tRNA translocation intermediates (class 3 of the six classes) | electron microscopy | A2 | — | — |
| 4V6V | Tetracycline resistance protein Tet(O) bound to the ribosome | electron microscopy | B4 | — | — |
| 5AKA | EM structure of ribosome-srp-ftsy complex in closed state | electron microscopy | Z | — | — |
| 5IQR | Structure of RelA bound to the 70S ribosome | electron microscopy | a | ZN | — |
| 5KCS | Cryo-EM structure of the Escherichia coli 70S ribosome in complex with antibiotic Evernimycin… | electron microscopy | 14 | — | — |
| 5KPW | Structure of RelA bound to ribosome in presence of A/R tRNA (Structure III) | electron microscopy | Z | — | — |
| 5L3P | Cryo-EM structure of stringent response factor RelA bound to ErmCL-stalled ribosome complex | electron microscopy | 4 | — | — |
| 5LZA | Structure of the 70S ribosome with SECIS-mRNA and P-site tRNA (Initial complex, IC) | electron microscopy | 6 | ZN | — |
| 5LZC | Structure of SelB-Sec-tRNASec bound to the 70S ribosome in the codon reading state (CR) | electron microscopy | 6 | ZN | — |
| 5LZE | Structure of the 70S ribosome with Sec-tRNASec in the classical pre-translocation state (C) | electron microscopy | 6 | ZN | — |
| 5MDV | Structure of ArfA and RF2 bound to the 70S ribosome (accommodated state) | electron microscopy | a | ZN | — |
| 5MDY | Structure of ArfA and TtRF2 bound to the 70S ribosome (pre-accommodated state) | electron microscopy | a | ZN | — |
| 5NWY | 2.9 A cryo-EM structure of VemP-stalled ribosome-nascent chain complex | electron microscopy | L | — | — |
| 5UYP | 70S ribosome bound with near-cognate ternary complex base-paired to A site codon, open 30S… | electron microscopy | 29 | — | — |
| 5WE4 | 70S ribosome-EF-Tu wt complex with GppNHp | electron microscopy | 6 | — | — |
| 5WE6 | 70S ribosome-EF-Tu H84A complex with GTP and cognate tRNA | electron microscopy | 6 | — | — |
| 6C4I | Conformation of methylated GGQ in the peptidyl transferase center during translation termination | electron microscopy | 1 | ZN | 1 (best 0.87) |
| 6H4N | Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein… | electron microscopy | 6 | — | — |
| 6H58 | Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein… | electron microscopy | 6, 66 | — | — |
| 6HRM | E. coli 70S d2d8 stapled ribosome | electron microscopy | a | ZN | — |
| 6Q97 | Structure of tmRNA SmpB bound in A site of E. coli 70S ribosome | electron microscopy | a | ZN | — |
| 6TC3 | Cryo-EM structure of an Escherichia coli ribosome-SpeFL complex stalled in response to L-ornithine… | electron microscopy | L311 | ZN | — |
| 6WNT | 50S ribosomal subunit without free 5S rRNA and perturbed ptc | electron microscopy | A | — | — |
| 6WNV | 70S ribosome without free 5S rRNA and with a perturbed PTC | electron microscopy | A | — | 1 (best 0.83) |
| 6WNW | Active 70S ribosome without free 5S rRNA and bound with A- and P- tRNA | electron microscopy | A | — | — |
| 7ACJ | Structure of translocated trans-translation complex on E. coli stalled ribosome. | electron microscopy | a | ZN | 1 (best 0.87) |
| 7BL2 | pre-50S-ObgE particle state 1 | electron microscopy | b | ZN | — |
| 7BL3 | pre-50S-ObgE particle state 2 | electron microscopy | b | ZN | 1 (best 0.81) |
| 7BL4 | In vitro reconstituted 50S-obge-gmppnp-rsfs particle | electron microscopy | d | ZN | — |
| 7BL5 | pre-50S-ObgE particle | electron microscopy | b | ZN | — |
| 7BL5 | Pre-50S-obge particle | electron microscopy | b | ZN | — |
| 7BL6 | 50S-obge-gmppnp particle | electron microscopy | d | ZN | — |
| 7D6Z | Molecular model of the cryo-EM structure of 70S ribosome in complex with peptide deformylase and… | electron microscopy | 6 | — | — |
| 7K50 | Pre-translocation non-frameshifting(CCA-A) complex (Structure I) | electron microscopy | A | — | 1 (best 0.83) |
| 7K54 | Mid-translocated +1-frameshifting(CCC-A) complex with EF-G and GDPCP (Structure II-FS) | electron microscopy | A | — | — |
| 7N2U | Elongating 70S ribosome complex in a hybrid-H1 pre-translocation (PRE-H1) conformation | electron microscopy | Le | ZN | — |
| 7N30 | Elongating 70S ribosome complex in a hybrid-H2* pre-translocation (PRE-H2*) conformation | electron microscopy | Le | — | 1 (best 0.87) |
| 7PJY | Structure of the 70S-EF-G-GDP ribosome complex with tRNAs in chimeric state 1 (CHI1-EF-G-GDP) | electron microscopy | 6 | MG, ZN | 1 (best 0.83) |
| 7Y7C | Structure of the Bacterial Ribosome with human tRNA Asp(G34) and mRNA(GAU) | electron microscopy | 4 | — | — |
| 8BHN | Elongating E. coli 70S ribosome containing deacylated tRNA(iMet) in the P-site and m6AAA mRNA codon… | electron microscopy | X | — | — |
12 records more on the page itself.
Ligands
Experiment against prediction
- 9FBV chain 4 against the predicted model P0A7M9: TM-score 0.83, RMSD 1.45 Å
- 8SYL chain 3 against the predicted model P0A7M9: TM-score 0.83, RMSD 1.46 Å
- 8G6X chain 4 against the predicted model P0A7M9: TM-score 0.81, RMSD 1.42 Å
- 8G6W chain 4 against the predicted model P0A7M9: TM-score 0.81, RMSD 1.51 Å
- 8YUQ chain 4 against the predicted model P0A7M9: TM-score 0.81, RMSD 1.56 Å
- 7Y7C chain 4 against the predicted model P0A7M9: TM-score 0.81, RMSD 1.60 Å
- 8EKC chain 3 against the predicted model P0A7M9: TM-score 0.77, RMSD 2.12 Å
- 8G7P chain 3 against the predicted model P0A7M9: TM-score 0.77, RMSD 1.85 Å
- 7BL3 chain b against the predicted model P0A7M9: TM-score 0.77, RMSD 1.68 Å
- 5IQR chain a against the predicted model P0A7M9: TM-score 0.77, RMSD 2.12 Å
Elsewhere
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