UniProt P0A7B5
Glutamate 5-kinase (P0A7B5)
Glutamate 5-kinase (UniProt P0A7B5), EC 2.7.2.11: 8 experimental structures and 1 predicted model on GenesisL1, 42 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0A7B5
- Protein
- Glutamate 5-kinase
- EC
- 2.7.2.11
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 42 · 3 records with a druggable one
Structures
9 records of P0A7B5 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2J5T | Glutamate 5-kinase from Escherichia coli complexed with glutamate | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 2J5T | Glutamate 5-kinase from escherichia COLI complexed with glutamate | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 2J5V | Glutamate 5-kinase from escherichia COLI complexed with glutamyl-5-phosphate and pyroglutamic acid | x-ray diffraction | A, B | — | — |
| 2J5V | Glutamate 5-kinase from escherichia COLI complexed with glutamyl-5-phosphate and pyroglutamic acid | x-ray diffraction | A, B | — | — |
| 2W21 | Crystal structure of the aminoacid kinase domain of the glutamate 5 kinase of Escherichia coli. | x-ray diffraction | A | — | — |
| 2W21 | Crystal structure of the aminoacid kinase domain of the glutamate 5 kinase of escherichia COLI. | x-ray diffraction | A | — | — |
| 8ZPJ | EcGK bundle at APO state. | electron microscopy | A, B, C, D, E, F, G, H | — | 20 (best 0.76) |
| 8ZRI | EcGK filament at APO state. | electron microscopy | A, B, C, D, E, F, G, H | — | 20 (best 0.77) |
| P0A7B5 | AlphaFold monomer V2.0 prediction for glutamate 5-kinase (P0A7B5) | predicted | A | — | 2 (best 0.69) |
Experiment against prediction
- 2J5T chain H against the predicted model P0A7B5: TM-score 0.99, RMSD 0.55 Å
- 2J5T chain H against the predicted model P0A7B5: TM-score 0.99, RMSD 0.55 Å
- 2J5V chain A against the predicted model P0A7B5: TM-score 0.99, RMSD 0.32 Å
- 2J5V chain A against the predicted model P0A7B5: TM-score 0.99, RMSD 0.32 Å
- 2J5T chain C against the predicted model P0A7B5: TM-score 0.99, RMSD 0.60 Å
- 2J5T chain C against the predicted model P0A7B5: TM-score 0.99, RMSD 0.60 Å
- 2J5T chain B against the predicted model P0A7B5: TM-score 0.99, RMSD 0.65 Å
- 2J5T chain B against the predicted model P0A7B5: TM-score 0.99, RMSD 0.65 Å
- 2J5V chain B against the predicted model P0A7B5: TM-score 0.99, RMSD 0.57 Å
- 2J5V chain B against the predicted model P0A7B5: TM-score 0.99, RMSD 0.57 Å
Elsewhere
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