UniProt P0A6F5
Chaperonin GroEL (P0A6F5)
Chaperonin GroEL (UniProt P0A6F5), EC 5.6.1.7: 110 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 476 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0A6F5
- Protein
- Chaperonin GroEL
- EC
- 5.6.1.7
- Experimental structures
- 110
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 476 · 28 records with a druggable one
Structures
111 records of P0A6F5 in the MolNFT archive: 110 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AON | Crystal structure of the asymmetric chaperonin complex GROEL/GROES/(ADP)7 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 1AON | Crystal structure of the asymmetric chaperonin complex GROEL/GROES/(ADP)7 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 1DK7 | Crystal structure of an isolated apical domain of groel | x-ray diffraction | A, B | — | — |
| 1DK7 | Crystal structure of an isolated apical domain of groel | x-ray diffraction | A, B | — | — |
| 1DKD | Crystal structure of a groel (apical domain) and a dodecameric peptide complex | x-ray diffraction | A, B, C, D | — | — |
| 1DKD | Crystal structure of a groel (apical domain) and a dodecameric peptide complex | x-ray diffraction | A, B, C, D | — | — |
| 1FY9 | Crystal structure of the hexa-substituted mutant of the molecular chaperonin groel apical domain | x-ray diffraction | A | — | — |
| 1FY9 | Crystal structure of the hexa-substituted mutant of the molecular chaperonin groel apical domain | x-ray diffraction | A | — | — |
| 1FYA | Crystal structure of the hexa-substituted mutant of the molecular chaperonin groel apical domain | x-ray diffraction | A | — | — |
| 1FYA | Crystal structure of the hexa-substituted mutant of the molecular chaperonin groel apical domain | x-ray diffraction | A | — | — |
| 1JON | Groel (HSP60 class) fragment comprising residues 191-345 | x-ray diffraction | A | — | — |
| 1JON | Groel (HSP60 class) fragment comprising residues 191-345 | x-ray diffraction | A | — | — |
| 1KID | Groel (HSP60 class) fragment (apical domain) comprising residues 191-376, mutant with ala 262… | x-ray diffraction | A | — | — |
| 1KID | Groel (HSP60 class) fragment (apical domain) comprising residues 191- 376, mutant with ala 262… | x-ray diffraction | A | — | — |
| 1KP8 | Structural Basis for GroEL-assisted Protein Folding from the Crystal Structure of (GroEL-KMgATP)14… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 1KP8 | Structural basis for groel-assisted protein folding from the crystal structure of (groel-KMGATP)14… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 1LA1 | Gro-EL Fragment (Apical Domain) Comprising Residues 188-379 | x-ray diffraction | A | — | — |
| 1LA1 | Gro-el fragment (apical domain) comprising residues 188-379 | x-ray diffraction | A | — | — |
| 1MNF | Domain motions in GroEL upon binding of an oligopeptide | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 1MNF | Domain motions in groel upon binding of an oligopeptide | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 1OEL | Conformational variability in the refined structure of the chaperonin groel at 2.8 ångström… | x-ray diffraction | A, B, C, D, E, F, G | — | — |
| 1OEL | Conformational variability in the refined structure of the chaperonin groel at 2.8 ångström… | x-ray diffraction | A, B, C, D, E, F, G | — | — |
| 1PCQ | Crystal structure of groEL-groES | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 1PCQ | Crystal structure of groel-groes | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 1SS8 | GroEL | x-ray diffraction | A, B, C, D, E, F, G | — | — |
| 1SS8 | GROEL | x-ray diffraction | A, B, C, D, E, F, G | — | — |
| 1SVT | Crystal structure of GroEL14-GroES7-(ADP-AlFx)7 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 1SVT | Crystal structure of GROEL14-GROES7-(ADP-ALFX)7 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 1SX3 | GroEL14-(ATPgammaS)14 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 1SX3 | GROEL14-(ATPGAMMAS)14 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 1SX4 | GroEL-GroES-ADP7 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 1SX4 | Groel-groes-ADP7 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 2C7C | Fitted coordinates for groel-ATP7-groes cryo-EM complex (emd-1180) | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 2C7C | Fitted coordinates for groel-ATP7-groes cryo-EM complex (emd-1180) | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 2C7D | Fitted coordinates for GroEL-ADP7-GroES Cryo-EM complex (EMD-1181) | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 2C7D | Fitted coordinates for groel-ADP7-groes cryo-EM complex (emd-1181) | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 2CGT | GROEL-ADP-gp31 COMPLEX | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 2CGT | Groel-ADP-GP31 complex | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 2EU1 | Crystal structure of the chaperonin GroEL-E461K | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 2EU1 | Crystal structure of the chaperonin groel-E461K | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 2YEY | Crystal structure of the allosteric-defective chaperonin GroEL E434K mutant | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 2YEY | Crystal structure of the allosteric-defective chaperonin groel E434K mutant | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 3C9V | C7 Symmetrized Structure of Unliganded GroEL at 4.7 Angstrom Resolution from CryoEM | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 3C9V | C7 symmetrized structure of unliganded groel at 4.7 ångström resolution from cryoem | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 3CAU | D7 symmetrized structure of unliganded GroEL at 4.2 Angstrom resolution by cryoEM | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 3CAU | D7 symmetrized structure of unliganded groel at 4.2 ångström resolution by cryoem | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 3VZ6 | Crystal Structure Analysis of the Mini-chaperonines, variant with Gly 184 replaced with Ile and Leu… | x-ray diffraction | A | — | — |
| 3VZ6 | Crystal structure analysis of the mini-chaperonines, variant with gly 184 replaced with ile and leu… | x-ray diffraction | A | — | — |
| 3VZ7 | Crystal Structure Analysis of the mini-chaperonin variant with Pro 187 Gly | x-ray diffraction | A | — | — |
| 3VZ7 | Crystal structure analysis of the mini-chaperonin variant with pro 187 gly | x-ray diffraction | A | — | — |
| 3VZ8 | Crystal Structure Analysis of the Mini-chaperonin variant with Leu 185, Val 186, Pro 187, Arg 188… | x-ray diffraction | A, B, C | — | — |
| 3VZ8 | Crystal structure analysis of the mini-chaperonin variant with leu 185, val 186, pro 187, arg 188… | x-ray diffraction | A, B, C | — | — |
| 3WVL | Crystal structure of the football-shaped GroEL-GroES complex (GroEL: GroES2:ATP14) from Escherichia… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 3WVL | Crystal structure of the football-shaped groel-groes complex (groel: GROES2:ATP14) from escherichia… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 3ZPZ | Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 3ZPZ | Visualizing groel-es in the act of encapsulating a non-native substrate protein | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 3ZQ0 | Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 3ZQ0 | Visualizing groel-es in the act of encapsulating a non-native substrate protein | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 3ZQ1 | Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 3ZQ1 | Visualizing groel-es in the act of encapsulating a non-native substrate protein | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
51 records more on the page itself.
Ligands
Experiment against prediction
- 1DKD chain B against the predicted model P0A6F5: TM-score 0.99, RMSD 0.51 Å
- 1DKD chain B against the predicted model P0A6F5: TM-score 0.99, RMSD 0.51 Å
- 1DKD chain A against the predicted model P0A6F5: TM-score 0.99, RMSD 0.55 Å
- 1DKD chain A against the predicted model P0A6F5: TM-score 0.99, RMSD 0.55 Å
- 1JON chain A against the predicted model P0A6F5: TM-score 0.99, RMSD 0.63 Å
- 1JON chain A against the predicted model P0A6F5: TM-score 0.99, RMSD 0.63 Å
- 1DKD chain D against the predicted model P0A6F5: TM-score 0.98, RMSD 0.61 Å
- 1DKD chain D against the predicted model P0A6F5: TM-score 0.98, RMSD 0.61 Å
- 1DKD chain C against the predicted model P0A6F5: TM-score 0.98, RMSD 0.65 Å
- 1DKD chain C against the predicted model P0A6F5: TM-score 0.98, RMSD 0.65 Å
Elsewhere
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