UniProt P0A5I7
Beta-lactamase (P0A5I7)
Beta-lactamase (UniProt P0A5I7), EC 3.5.2.6: 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0A5I7
- Protein
- Beta-lactamase
- EC
- 3.5.2.6
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 12 · 2 records with a druggable one
Structures
4 records of P0A5I7 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6H27 | Structure of S70C BlaC from Mycobacterium tuberculosis | x-ray diffraction | A, B | — | 3 (best 0.56) |
| 6H27 | Structure of S70C blac from mycobacterium tuberculosis | x-ray diffraction | A, B | — | — |
| 8GCS | XFEL structure of Mycobacterium tuberculosis beta lactamase microcrystals mixed with sulbactam for… | x-ray diffraction | A, B, C, D | PO4 | 9 (best 0.73) |
| P0A5I7 | AlphaFold monomer V2.0 prediction for beta-lactamase (P0A5I7) | predicted | A | — | — |
Ligands
- PO4 · Phosphate ion · in 1 record
Experiment against prediction
- 8GCS chain B against the predicted model P0A5I7: TM-score 0.99, RMSD 0.72 Å
- 8GCS chain D against the predicted model P0A5I7: TM-score 0.99, RMSD 0.73 Å
- 8GCS chain A against the predicted model P0A5I7: TM-score 0.99, RMSD 0.73 Å
- 8GCS chain C against the predicted model P0A5I7: TM-score 0.99, RMSD 0.76 Å
- 6H27 chain B against the predicted model P0A5I7: TM-score 0.99, RMSD 0.53 Å
- 6H27 chain B against the predicted model P0A5I7: TM-score 0.99, RMSD 0.53 Å
- 6H27 chain A against the predicted model P0A5I7: TM-score 0.98, RMSD 0.47 Å
- 6H27 chain A against the predicted model P0A5I7: TM-score 0.98, RMSD 0.47 Å
Elsewhere
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