UniProt P0A4T9
Hth-type transcriptional activator tipa (P0A4T9)
Hth-type transcriptional activator tipa (UniProt P0A4T9): 8 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0A4T9
- Protein
- Hth-type transcriptional activator tipa
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
9 records of P0A4T9 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1NY9 | Antibiotic binding domain of a TipA-class multidrug resistance transcriptional regulator | solution nmr | A | — | 1 (best 0.44) |
| 1NY9 | Antibiotic binding domain of a tipa-class multidrug resistance transcriptional regulator | solution nmr | A | — | — |
| 2MBZ | Structural Basis of a Thiopeptide Antibiotic Multidrug Resistance System from Streptomyces… | solution nmr | A | — | — |
| 2MBZ | Structural basis of a thiopeptide antibiotic multidrug resistance system from streptomyces… | solution nmr | A | — | — |
| 2MC0 | Structural Basis of a Thiopeptide Antibiotic Multidrug Resistance System from Streptomyces… | solution nmr | A | — | — |
| 2MC0 | Structural basis of a thiopeptide antibiotic multidrug resistance system from streptomyces… | solution nmr | A | — | — |
| 2VZ4 | The N-terminal domain of MerR-like protein TipAL bound to promoter DNA | x-ray diffraction | A | — | — |
| 2VZ4 | The N-terminal domain of merr-like protein tipal bound to promoter DNA | x-ray diffraction | A | — | — |
| P0A4T9 | AlphaFold monomer V2.0 prediction for hth-type transcriptional activator tipa (P0A4T9) | predicted | A | — | 1 (best 0.81) |
Experiment against prediction
- 2MBZ chain A against the predicted model P0A4T9: TM-score 0.92, RMSD 1.44 Å
- 2MBZ chain A against the predicted model P0A4T9: TM-score 0.92, RMSD 1.44 Å
- 2MC0 chain A against the predicted model P0A4T9: TM-score 0.91, RMSD 1.47 Å
- 2MC0 chain A against the predicted model P0A4T9: TM-score 0.91, RMSD 1.47 Å
- 1NY9 chain A against the predicted model P0A4T9: TM-score 0.88, RMSD 1.62 Å
- 1NY9 chain A against the predicted model P0A4T9: TM-score 0.88, RMSD 1.62 Å
- 2VZ4 chain A against the predicted model P0A4T9: TM-score 0.73, RMSD 2.55 Å
- 2VZ4 chain A against the predicted model P0A4T9: TM-score 0.73, RMSD 2.55 Å
Elsewhere
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