UniProt P0A1P6
Glutamine synthetase (P0A1P6)
Glutamine synthetase (UniProt P0A1P6), EC 6.3.1.2: 8 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 160 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0A1P6
- Protein
- Glutamine synthetase
- EC
- 6.3.1.2
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 160 · 8 records with a druggable one
Structures
9 records of P0A1P6 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1F1H | Crystal structure of glutamine synthetase from salmonella typhimurium with thallium ions | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | MN, ADP, TL | 20 (best 0.83) |
| 1F1H | Crystal structure of glutamine synthetase from salmonella typhimurium with thallium ions | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | MN, ADP, TL | 20 (best 0.83) |
| 1F52 | Crystal structure of glutamine synthetase from salmonella typhimurium co-crystallized with ADP | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | MN, ADP | 20 (best 0.82) |
| 1F52 | Crystal structure of glutamine synthetase from salmonella typhimurium co-crystallized with ADP | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | MN, ADP | 20 (best 0.82) |
| 1FPY | Crystal structure of glutamine synthetase from salmonella typhimurium with inhibitor… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | MN, ADP, PPQ | 20 (best 0.79) |
| 1FPY | Crystal structure of glutamine synthetase from salmonella typhimurium with inhibitor… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | MN, ADP, PPQ | 20 (best 0.79) |
| 2GLS | Refined atomic model of glutamine synthetase at 3.5 ångströms resolution | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | MN | 20 (best 0.81) |
| 2GLS | Refined atomic model of glutamine synthetase at 3.5 ångströms resolution | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | MN | 20 (best 0.81) |
| P0A1P6 | AlphaFold monomer V2.0 prediction for glutamine synthetase (P0A1P6) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1F52 chain A against the predicted model P0A1P6: TM-score 0.99, RMSD 0.69 Å
- 1F52 chain A against the predicted model P0A1P6: TM-score 0.99, RMSD 0.69 Å
- 1FPY chain A against the predicted model P0A1P6: TM-score 0.99, RMSD 0.68 Å
- 1FPY chain A against the predicted model P0A1P6: TM-score 0.99, RMSD 0.68 Å
- 1F1H chain A against the predicted model P0A1P6: TM-score 0.99, RMSD 0.72 Å
- 1F1H chain A against the predicted model P0A1P6: TM-score 0.99, RMSD 0.72 Å
- 2GLS chain A against the predicted model P0A1P6: TM-score 0.97, RMSD 1.18 Å
- 2GLS chain A against the predicted model P0A1P6: TM-score 0.97, RMSD 1.18 Å
Elsewhere
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