UniProt P09950
5-aminolevulinate synthase, mitochondrial (P09950)
5-aminolevulinate synthase, mitochondrial (UniProt P09950), EC 2.3.1.37: 6 experimental structures on GenesisL1, 3 ligands bound, 41 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P09950
- Protein
- 5-aminolevulinate synthase, mitochondrial
- EC
- 2.3.1.37
- Experimental structures
- 6
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 41 · 3 records with a druggable one
Structures
6 records of P09950 in the MolNFT archive: 6 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5TXR | Structure of ALAS from S. cerevisiae non-covalently bound to PLP cofactor | x-ray diffraction | B, A | PLP, K | 11 (best 0.79) |
| 5TXR | Structure of alas from S. cerevisiae non-covalently bound to plp cofactor | x-ray diffraction | B, A | PLP, K | — |
| 5TXT | Structure of asymmetric apo/holo ALAS dimer from S. cerevisiae | x-ray diffraction | A, B, D, C, E, F | SO4 | 20 (best 0.81) |
| 5TXT | Structure of asymmetric APO/HOLO alas dimer from S. cerevisiae | x-ray diffraction | A, B, D, C, E, F | SO4 | — |
| 8EIM | Structure of ALAS with C-terminal truncation from S. cerevisiae | x-ray diffraction | A, B | PLP | 10 (best 0.76) |
| P09950 | AlphaFold monomer V2.0 prediction for 5-aminolevulinate synthase, mitochondrial (P09950) | — | — | — |
Ligands
Elsewhere
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