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UniProt P09668

Pro-cathepsin H (P09668)

Pro-cathepsin H (UniProt P09668), EC 3.4.22.16: 4 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P09668
Protein
Pro-cathepsin H
EC
3.4.22.16
Experimental structures
4
Predicted models
1
Ligands
6
Pockets
3 · 0 records with a druggable one

Structures

5 records of P09668 in the MolNFT archive: 4 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
6CZKCrystal structure of wild-type human pro-cathepsin Hx-ray diffractionANAG, BMA, MAN, SO42 (best 0.40)
6CZKCrystal structure of wild-type human pro-cathepsin Hx-ray diffractionANAG, BMA, SO4—
6CZSCrystal structure of human pro-cathepsin H C26S mutantx-ray diffractionANAG, BMA, GLC, SO4, CL1 (best 0.42)
6CZSCrystal structure of human pro-cathepsin H C26S mutantx-ray diffractionANAG, BMA, GLC, SO4, CL—
P09668AlphaFold monomer V2.0 prediction for pro-cathepsin H (P09668)predictedA——

Ligands

  • BMA · beta-D-mannopyranose · in 4 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
  • SO4 · Sulfate ion · in 4 records
  • CL · Chloride ion · in 2 records
  • GLC · alpha-D-glucopyranose · in 2 records
  • MAN · alpha-D-mannopyranose · in 1 record

Experiment against prediction

Elsewhere

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