UniProt P08510
Potassium voltage-gated channel protein Shaker (P08510)
Potassium voltage-gated channel protein Shaker (UniProt P08510): 9 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 44 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P08510
- Protein
- Potassium voltage-gated channel protein Shaker
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 44 · 4 records with a druggable one
Structures
10 records of P08510 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1HO2 | NMR structure of the potassium channel fragment L45 in micelles | solution nmr | A | — | — |
| 1HO2 | NMR structure of the potassium channel fragment L45 in micelles | solution nmr | A | — | — |
| 1HO7 | NMR structure of the potassium channel fragment L45 in tfe | solution nmr | A | — | — |
| 1HO7 | NMR structure of the potassium channel fragment L45 in tfe | solution nmr | A | — | — |
| 7SIP | Structure of shaker-IR | electron microscopy | A, B, C, D | POV, K | 18 (best 0.80) |
| 7SIP | Structure of shaker-ir | electron microscopy | A, B, C, D | POV, K | — |
| 7SJ1 | Structure of shaker-W434F | electron microscopy | A, B, C, D | POV, K | 15 (best 0.80) |
| 7SJ1 | Structure of shaker-W434F | electron microscopy | A, B, C, D | POV, K | — |
| 8TEO | Shaker in low K+ (4mM K+) | electron microscopy | A, B, C, D | POV, K | 8 (best 0.83) |
| P08510 | AlphaFold monomer V2.0 prediction for potassium voltage-gated channel protein shaker (P08510) | predicted | A | — | 3 (best 0.64) |
Ligands
Experiment against prediction
- 8TEO chain D against the predicted model P08510: TM-score 0.97, RMSD 1.19 Å
- 8TEO chain B against the predicted model P08510: TM-score 0.97, RMSD 1.19 Å
- 8TEO chain C against the predicted model P08510: TM-score 0.97, RMSD 1.19 Å
- 8TEO chain A against the predicted model P08510: TM-score 0.97, RMSD 1.19 Å
- 7SIP chain C against the predicted model P08510: TM-score 0.96, RMSD 1.20 Å
- 7SIP chain B against the predicted model P08510: TM-score 0.96, RMSD 1.20 Å
- 7SIP chain A against the predicted model P08510: TM-score 0.96, RMSD 1.20 Å
- 7SIP chain A against the predicted model P08510: TM-score 0.96, RMSD 1.20 Å
- 7SIP chain D against the predicted model P08510: TM-score 0.96, RMSD 1.20 Å
- 7SJ1 chain C against the predicted model P08510: TM-score 0.94, RMSD 1.54 Å
Elsewhere
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