UniProt P08483
Muscarinic acetylcholine receptor M3,Endolysin,Endolysin,Muscarinic acetylcholine receptor M3 (P08483)
Muscarinic acetylcholine receptor M3,Endolysin,Endolysin,Muscarinic acetylcholine receptor M3 (UniProt P08483), EC 3.2.1.17: 10 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 10 pockets. Binding…
- UniProt
- P08483
- Protein
- Muscarinic acetylcholine receptor M3,Endolysin,Endolysin,Muscarinic…
- EC
- 3.2.1.17
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 10 · 1 record with a druggable one
Structures
11 records of P08483 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4DAJ | Structure of the M3 Muscarinic Acetylcholine Receptor | x-ray diffraction | A, B, C, D | — | — |
| 4DAJ | Structure of the M3 muscarinic acetylcholine receptor | x-ray diffraction | A, B, C, D | — | — |
| 4U14 | Structure of the M3 muscarinic acetylcholine receptor bound to the antagonist tiotropium… | x-ray diffraction | A | — | — |
| 4U14 | Structure of the M3 muscarinic acetylcholine receptor bound to the antagonist tiotropium… | x-ray diffraction | A | — | — |
| 4U15 | M3-mT4L receptor bound to tiotropium | x-ray diffraction | A, B | — | — |
| 4U15 | M3-MT4L receptor bound to tiotropium | x-ray diffraction | A, B | — | — |
| 4U16 | M3-mT4L receptor bound to NMS | x-ray diffraction | A, B | — | — |
| 4U16 | M3-MT4L receptor bound to nms | x-ray diffraction | A, B | — | — |
| 5ZHP | M3 muscarinic acetylcholine receptor in complex with a selective antagonist | x-ray diffraction | A, B | GLC, 9EC | 10 (best 0.80) |
| 5ZHP | M3 muscarinic acetylcholine receptor in complex with a selective antagonist | x-ray diffraction | A, B | GLC, 9EC | — |
| P08483 | AlphaFold monomer V2.0 prediction for muscarinic acetylcholine receptor M3 (P08483) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5ZHP chain B against the predicted model P08483: TM-score 0.75, RMSD 3.50 Å
- 5ZHP chain B against the predicted model P08483: TM-score 0.75, RMSD 3.50 Å
- 4U15 chain B against the predicted model P08483: TM-score 0.74, RMSD 3.32 Å
- 4U15 chain B against the predicted model P08483: TM-score 0.74, RMSD 3.32 Å
- 4U16 chain B against the predicted model P08483: TM-score 0.74, RMSD 3.43 Å
- 4U16 chain B against the predicted model P08483: TM-score 0.74, RMSD 3.43 Å
- 5ZHP chain A against the predicted model P08483: TM-score 0.74, RMSD 3.39 Å
- 5ZHP chain A against the predicted model P08483: TM-score 0.74, RMSD 3.39 Å
- 4U15 chain A against the predicted model P08483: TM-score 0.73, RMSD 3.39 Å
- 4U15 chain A against the predicted model P08483: TM-score 0.73, RMSD 3.39 Å
Elsewhere
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