UniProt P08144
Alpha-amylase A (P08144)
Alpha-amylase A (UniProt P08144), EC 3.2.1.1: 2 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P08144
- Protein
- Alpha-amylase A
- EC
- 3.2.1.1
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 10 · 2 records with a druggable one
Structures
3 records of P08144 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8OR6 | Crystal structure of Drosophila melanogaster alpha-amylase | x-ray diffraction | A, B | CL, SR | 5 (best 0.61) |
| 8ORP | Crystal structure of Drosophila melanogaster alpha-amylase in complex with the inhibitor acarbose | x-ray diffraction | A, B | BGC, GLC, RY7, CL, SR | 5 (best 0.62) |
| P08144 | AlphaFold monomer V2.0 prediction for alpha-amylase a (P08144) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8ORP chain B against the predicted model P08144: TM-score 1.00, RMSD 0.44 Å
- 8ORP chain A against the predicted model P08144: TM-score 1.00, RMSD 0.48 Å
- 8OR6 chain B against the predicted model P08144: TM-score 0.99, RMSD 0.57 Å
- 8OR6 chain A against the predicted model P08144: TM-score 0.99, RMSD 0.60 Å
Elsewhere
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