UniProt P07686
Beta-hexosaminidase subunit beta (P07686)
Beta-hexosaminidase subunit beta (UniProt P07686), EC 3.2.1.52: 16 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P07686
- Protein
- Beta-hexosaminidase subunit beta
- EC
- 3.2.1.52
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
17 records of P07686 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1NOU | Native human lysosomal beta-hexosaminidase isoform B | x-ray diffraction | A, B | — | — |
| 1NOU | Native human lysosomal beta-hexosaminidase isoform B | x-ray diffraction | A, B | — | — |
| 1NOW | Human lysosomal beta-hexosaminidase isoform B in complex with… | x-ray diffraction | A, B | — | — |
| 1NOW | Human lysosomal beta-hexosaminidase isoform B in complex with (2R,3R… | x-ray diffraction | A, B | — | — |
| 1NP0 | Human lysosomal beta-hexosaminidase isoform B in complex with intermediate analogue NAG-thiazoline | x-ray diffraction | A, C, D, B, E, F | — | — |
| 1NP0 | Human lysosomal beta-hexosaminidase isoform B in complex with intermediate analogue nag-thiazoline | x-ray diffraction | A, C, D, B, E, F | — | — |
| 1O7A | Human beta-Hexosaminidase B | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1O7A | Human beta-hexosaminidase B | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2GJX | Crystallographic structure of human beta-Hexosaminidase A | x-ray diffraction | B, C, F, G | — | — |
| 2GJX | Crystallographic structure of human beta-hexosaminidase a | x-ray diffraction | B, C, F, G | — | — |
| 2GK1 | X-ray crystal structure of NGT-bound HexA | x-ray diffraction | B, M, N, D, O, P, F, Q, R, H, S, T | — | — |
| 2GK1 | X-ray crystal structure of ngt-bound hexa | x-ray diffraction | B, M, N, D, O, P, F, Q, R, H, S, T | — | — |
| 3LMY | The Crystal Structure of beta-hexosaminidase B in complex with Pyrimethamine | x-ray diffraction | A, B | — | — |
| 3LMY | The crystal structure of beta-hexosaminidase B in complex with pyrimethamine | x-ray diffraction | A, B | — | — |
| 5BRO | Crystal structure of modified HexB (modB) | x-ray diffraction | A | NAG | 3 (best 0.54) |
| 5BRO | Crystal structure of modified hexb (modb) | x-ray diffraction | A | — | — |
| P07686 | AlphaFold monomer V2.0 prediction for beta-hexosaminidase subunit beta (P07686) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 1 record
Experiment against prediction
- 5BRO chain A against the predicted model P07686: TM-score 1.00, RMSD 0.45 Å
- 5BRO chain A against the predicted model P07686: TM-score 1.00, RMSD 0.45 Å
- 1O7A chain D against the predicted model P07686: TM-score 1.00, RMSD 0.43 Å
- 1O7A chain D against the predicted model P07686: TM-score 1.00, RMSD 0.43 Å
- 1O7A chain A against the predicted model P07686: TM-score 1.00, RMSD 0.45 Å
- 1O7A chain A against the predicted model P07686: TM-score 1.00, RMSD 0.45 Å
- 1NP0 chain C against the predicted model P07686: TM-score 1.00, RMSD 0.31 Å
- 1NP0 chain C against the predicted model P07686: TM-score 1.00, RMSD 0.31 Å
- 3LMY chain A against the predicted model P07686: TM-score 1.00, RMSD 0.49 Å
- 3LMY chain A against the predicted model P07686: TM-score 1.00, RMSD 0.49 Å
Elsewhere
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