UniProt P07360
Complement component C8 gamma chain (P07360)
Complement component C8 gamma chain (UniProt P07360): 14 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P07360
- Protein
- Complement component C8 gamma chain
- Experimental structures
- 14
- Predicted models
- 1
- Pockets
- 2 · 2 records with a druggable one
Structures
15 records of P07360 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1IW2 | X-ray structure of Human Complement Protein C8gamma at pH=7.O | x-ray diffraction | A | — | — |
| 1IW2 | X-ray structure of human complement protein C8GAMMA at PH=7.O | x-ray diffraction | A | — | — |
| 1LF7 | Crystal Structure of Human Complement Protein C8gamma at 1.2 A Resolution | x-ray diffraction | A | — | — |
| 1LF7 | Crystal structure of human complement protein C8GAMMA at 1.2 a resolution | x-ray diffraction | A | — | — |
| 2RD7 | Human Complement Membrane Attack Proteins Share a Common Fold with Bacterial Cytolysins | x-ray diffraction | C | — | — |
| 2RD7 | Human complement membrane attack proteins share a common fold with bacterial cytolysins | x-ray diffraction | C | — | — |
| 3OJY | Crystal Structure of Human Complement Component C8 | x-ray diffraction | C | — | — |
| 3OJY | Crystal structure of human complement component C8 | x-ray diffraction | C | — | — |
| 6H03 | Open conformation of the membrane attack complex | electron microscopy | E | — | — |
| 6H04 | Closed conformation of the Membrane Attack Complex | electron microscopy | E | — | — |
| 6H04 | Closed conformation of the membrane attack complex | electron microscopy | E | — | — |
| 7NYC | Cryoem structure of 3C9-smac | electron microscopy | F | — | — |
| 8B0G | 2C9, C5b9-CD59 structure | electron microscopy | F | — | 1 (best 0.86) |
| 8B0H | 2C9, C5b9-CD59 cryoEM structure | electron microscopy | F | — | 1 (best 0.85) |
| P07360 | AlphaFold monomer V2.0 prediction for complement component C8 gamma chain (P07360) | predicted | A | — | — |
Experiment against prediction
- 2RD7 chain C against the predicted model P07360: TM-score 0.98, RMSD 0.71 Å
- 2RD7 chain C against the predicted model P07360: TM-score 0.98, RMSD 0.71 Å
- 1IW2 chain A against the predicted model P07360: TM-score 0.98, RMSD 0.79 Å
- 1IW2 chain A against the predicted model P07360: TM-score 0.98, RMSD 0.79 Å
- 3OJY chain C against the predicted model P07360: TM-score 0.98, RMSD 0.78 Å
- 3OJY chain C against the predicted model P07360: TM-score 0.98, RMSD 0.78 Å
- 6H03 chain E against the predicted model P07360: TM-score 0.97, RMSD 0.79 Å
- 6H04 chain E against the predicted model P07360: TM-score 0.97, RMSD 0.81 Å
- 6H04 chain E against the predicted model P07360: TM-score 0.97, RMSD 0.81 Å
- 1LF7 chain A against the predicted model P07360: TM-score 0.97, RMSD 0.96 Å
Elsewhere
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