UniProt P07275
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (P07275)
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (UniProt P07275), EC 1.2.1.88: 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 42 pockets. Binding sites, druggability and experiment…
- UniProt
- P07275
- Protein
- Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
- EC
- 1.2.1.88
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 42 · 5 records with a druggable one
Structures
5 records of P07275 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4OE4 | Crystal Structure of Yeast ALDH4A1 Complexed with NAD+ | x-ray diffraction | A, B | NAD | 9 (best 0.77) |
| 4OE4 | Crystal structure of yeast ALDH4A1 complexed with NAD+ | x-ray diffraction | A, B | NAD | 9 (best 0.77) |
| 4OE6 | Crystal Structure of Yeast ALDH4A1 | x-ray diffraction | A, B | — | 10 (best 0.77) |
| 4OE6 | Crystal structure of yeast ALDH4A1 | x-ray diffraction | A, B | — | 10 (best 0.77) |
| P07275 | AlphaFold monomer V2.0 prediction for delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial… | predicted | A | — | 4 (best 0.72) |
Ligands
- NAD · Nicotinamide-adenine-dinucleotide · in 2 records
Experiment against prediction
- 4OE4 chain A against the predicted model P07275: TM-score 0.98, RMSD 1.10 Å
- 4OE4 chain A against the predicted model P07275: TM-score 0.98, RMSD 1.10 Å
- 4OE4 chain B against the predicted model P07275: TM-score 0.98, RMSD 1.16 Å
- 4OE4 chain B against the predicted model P07275: TM-score 0.98, RMSD 1.16 Å
- 4OE6 chain A against the predicted model P07275: TM-score 0.98, RMSD 1.39 Å
- 4OE6 chain A against the predicted model P07275: TM-score 0.98, RMSD 1.39 Å
- 4OE6 chain B against the predicted model P07275: TM-score 0.98, RMSD 1.42 Å
- 4OE6 chain B against the predicted model P07275: TM-score 0.98, RMSD 1.42 Å
Elsewhere
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