UniProt P07199
Major centromere autoantigen B (P07199)
Major centromere autoantigen B (UniProt P07199): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P07199
- Protein
- Major centromere autoantigen B
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 4 · 0 records with a druggable one
Structures
9 records of P07199 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BW6 | Human centromere protein B (cenp-B) DNA bindign domain RP1 | solution nmr | A | — | — |
| 1BW6 | Human centromere protein B (cenp-B) DNA bindign domain RP1 | solution nmr | A | — | — |
| 1HLV | Crystal structure of cenp-B(1-129) complexed with the cenp-B box DNA | x-ray diffraction | A | — | 3 (best 0.34) |
| 1HLV | Crystal structure of cenp-B(1-129) complexed with the cenp- B box DNA | x-ray diffraction | A | — | — |
| 1UFI | Crystal structure of the dimerization domain of human CENP-B | x-ray diffraction | A, B, C, D | — | 1 (best 0.40) |
| 1UFI | Crystal structure of the dimerization domain of human cenp-B | x-ray diffraction | A, B, C, D | — | — |
| 6KDR | Crystal structure of human NRMT2 in complex with human centromere protein B peptide | x-ray diffraction | D, E | CL | — |
| 6KDR | Crystal structure of human NRMT2 in complex with human centromere protein B peptide | x-ray diffraction | D, E | CL | — |
| P07199 | AlphaFold monomer V2.0 prediction for major centromere autoantigen B (P07199) | predicted | A | — | — |
Ligands
- CL · Chloride ion · in 2 records
Experiment against prediction
- 1UFI chain B against the predicted model P07199: TM-score 0.86, RMSD 0.96 Å
- 1UFI chain B against the predicted model P07199: TM-score 0.86, RMSD 0.96 Å
- 1UFI chain D against the predicted model P07199: TM-score 0.85, RMSD 1.01 Å
- 1UFI chain D against the predicted model P07199: TM-score 0.85, RMSD 1.01 Å
- 1UFI chain A against the predicted model P07199: TM-score 0.83, RMSD 1.39 Å
- 1UFI chain A against the predicted model P07199: TM-score 0.83, RMSD 1.39 Å
- 1UFI chain C against the predicted model P07199: TM-score 0.80, RMSD 1.53 Å
- 1UFI chain C against the predicted model P07199: TM-score 0.80, RMSD 1.53 Å
- 1HLV chain A against the predicted model P07199: TM-score 0.77, RMSD 2.60 Å
- 1HLV chain A against the predicted model P07199: TM-score 0.77, RMSD 2.60 Å
Elsewhere
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