UniProt P07003
Pyruvate dehydrogenase [ubiquinone] (P07003)
Pyruvate dehydrogenase [ubiquinone] (UniProt P07003): 4 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P07003
- Protein
- Pyruvate dehydrogenase [ubiquinone]
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
5 records of P07003 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3EY9 | Structural basis for membrane binding and catalytic activation of the peripheral membrane enzyme… | x-ray diffraction | A, B | — | — |
| 3EY9 | Structural basis for membrane binding and catalytic activation of the peripheral membrane enzyme… | x-ray diffraction | A, B | — | — |
| 3EYA | Structural basis for membrane binding and catalytic activation of the peripheral membrane enzyme… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 3EYA | Structural basis for membrane binding and catalytic activation of the peripheral membrane enzyme… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| P07003 | AlphaFold monomer V2.0 prediction for pyruvate dehydrogenase [ubiquinone] (P07003) | predicted | A | — | 5 (best 0.75) |
Experiment against prediction
- 3EYA chain D against the predicted model P07003: TM-score 0.99, RMSD 0.59 Å
- 3EYA chain D against the predicted model P07003: TM-score 0.99, RMSD 0.59 Å
- 3EYA chain G against the predicted model P07003: TM-score 0.99, RMSD 0.71 Å
- 3EYA chain G against the predicted model P07003: TM-score 0.99, RMSD 0.71 Å
- 3EYA chain J against the predicted model P07003: TM-score 0.99, RMSD 0.76 Å
- 3EYA chain J against the predicted model P07003: TM-score 0.99, RMSD 0.76 Å
- 3EYA chain C against the predicted model P07003: TM-score 0.99, RMSD 0.74 Å
- 3EYA chain C against the predicted model P07003: TM-score 0.99, RMSD 0.74 Å
- 3EYA chain B against the predicted model P07003: TM-score 0.99, RMSD 0.79 Å
- 3EYA chain B against the predicted model P07003: TM-score 0.99, RMSD 0.79 Å
Elsewhere
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