UniProt P06748
Nucleophosmin (P06748)
Nucleophosmin (UniProt P06748): 14 experimental structures on GenesisL1, 2 ligands bound, 23 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P06748
- Protein
- Nucleophosmin
- Experimental structures
- 14
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 23 · 4 records with a druggable one
Structures
14 records of P06748 in the MolNFT archive: 14 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2LLH | NMR structure of Npm1_c70 | solution nmr | A | — | — |
| 2LLH | NMR structure of NPM1_C70 | solution nmr | A | — | — |
| 2P1B | Crystal structure of human nucleophosmin-core | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2P1B | Crystal structure of human nucleophosmin-core | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 2VXD | The structure of the C-terminal domain of Nucleophosmin | solution nmr | A | — | — |
| 2VXD | The structure of the C-terminal domain of nucleophosmin | solution nmr | A | — | — |
| 5EHD | Crystal structure of human nucleophosmin-core in complex with cytochrome c | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, a, b, c, d, e, f, g, h, i, j | CL | 15 (best 0.89) |
| 5EHD | Crystal structure of human nucleophosmin-core in complex with cytochrome C | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, a, b, c, d, e, f, g, h, i, j | — | — |
| 7OBG | Crystal structure of 14-3-3 sigma in complex with NPM1 phosphopeptide | x-ray diffraction | B | — | 2 (best 0.55) |
| 7OBG | Crystal structure of 14-3-3 sigma in complex with NPM1 phosphopeptide | x-ray diffraction | B | — | — |
| 7OBH | Crystal structure of 14-3-3 sigma in complex with NPM1 phosphopeptide and stabilizer Fusicoccin-A | x-ray diffraction | B | FSC | 1 (best 0.57) |
| 7OBH | Crystal structure of 14-3-3 sigma in complex with NPM1 phosphopeptide and stabilizer fusicoccin-a | x-ray diffraction | B | FSC | — |
| 8AH2 | Crystal structure of human 14-3-3 zeta fused to the NPM1 peptide including phosphoserine-48 | x-ray diffraction | A, C | — | 5 (best 0.63) |
| P06748 | AlphaFold monomer V2.0 prediction for nucleophosmin (P06748) | — | — | — |
Ligands
Experiment against prediction
- 8AH2 chain C against the predicted model P63104: TM-score 0.95, RMSD 1.08 Å
- 8AH2 chain A against the predicted model P63104: TM-score 0.94, RMSD 1.12 Å
Elsewhere
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