UniProt P06400
Retinoblastoma-associated protein (P06400)
Retinoblastoma-associated protein (UniProt P06400): 26 experimental structures and 1 predicted model on GenesisL1, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P06400
- Protein
- Retinoblastoma-associated protein
- Experimental structures
- 26
- Predicted models
- 1
- Pockets
- 15 · 1 record with a druggable one
Structures
27 records of P06400 in the MolNFT archive: 26 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AD6 | Domain a of human retinoblastoma tumor suppressor | x-ray diffraction | A | — | — |
| 1AD6 | Domain a of human retinoblastoma tumor suppressor | x-ray diffraction | A | — | — |
| 1GH6 | Retinoblastoma pocket complexed with SV40 large T antigen | x-ray diffraction | B | — | — |
| 1GH6 | Retinoblastoma pocket complexed with SV40 large T antigen | x-ray diffraction | B | — | — |
| 1GUX | Rb pocket bound to E7 lxcxe motif | x-ray diffraction | A, B | — | — |
| 1GUX | Rb pocket bound to E7 lxcxe motif | x-ray diffraction | A, B | — | — |
| 1H25 | CDK2/Cyclin A in complex with an 11-residue recruitment peptide from retinoblastoma-associated… | x-ray diffraction | E | — | — |
| 1H25 | CDK2/CYCLIN a in complex with an 11-residue recruitment peptide from retinoblastoma-associated… | x-ray diffraction | E | — | — |
| 1O9K | Crystal structure of the retinoblastoma tumour suppressor protein bound to E2F peptide | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 1O9K | Crystal structure of the retinoblastoma tumour suppressor protein bound to E2F peptide | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 1PJM | Mouse Importin alpha-bipartite NLS from human retinoblastoma protein Complex | x-ray diffraction | A | — | — |
| 1PJM | Mouse importin alpha-bipartite nls from human retinoblastoma protein complex | x-ray diffraction | A | — | — |
| 2AZE | Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer | x-ray diffraction | C | — | — |
| 2AZE | Structure of the rb C-terminal domain bound to an E2F1-DP1 heterodimer | x-ray diffraction | C | — | — |
| 2QDJ | Crystal structure of the Retinoblastoma protein N-domain provides insight into tumor suppression… | x-ray diffraction | A | — | — |
| 2QDJ | Crystal structure of the retinoblastoma protein N-domain provides insight into tumor suppression… | x-ray diffraction | A | — | — |
| 2R7G | Structure of the retinoblastoma protein pocket domain in complex with adenovirus E1A CR1 domain | x-ray diffraction | A, C | — | — |
| 2R7G | Structure of the retinoblastoma protein pocket domain in complex with adenovirus E1A CR1 domain | x-ray diffraction | A, C | — | — |
| 3N5U | Crystal structure of an Rb C-terminal peptide bound to the catalytic subunit of PP1 | x-ray diffraction | C | — | — |
| 3N5U | Crystal structure of an rb C-terminal peptide bound to the catalytic subunit of PP1 | x-ray diffraction | C | — | — |
| 3POM | Crystal Structure of the Unliganded Retinoblastoma Protein Pocket Domain | x-ray diffraction | A, B | — | — |
| 3POM | Crystal structure of the unliganded retinoblastoma protein pocket domain | x-ray diffraction | A, B | — | — |
| 4ELJ | Crystal structure of the inactive retinoblastoma protein phosphorylated at T373 | x-ray diffraction | A | — | — |
| 4ELJ | Crystal structure of the inactive retinoblastoma protein phosphorylated at T373 | x-ray diffraction | A | — | — |
| 4ELL | Structure of the inactive retinoblastoma protein pocket domain | x-ray diffraction | A, B | — | — |
| 4ELL | Structure of the inactive retinoblastoma protein pocket domain | x-ray diffraction | A, B | — | — |
| P06400 | AlphaFold monomer V2.0 prediction for retinoblastoma-associated protein (P06400) | predicted | A | — | 15 (best 0.80) |
Experiment against prediction
- 3POM chain B against the predicted model P06400: TM-score 0.98, RMSD 1.10 Å
- 3POM chain B against the predicted model P06400: TM-score 0.98, RMSD 1.10 Å
- 1GUX chain B against the predicted model P06400: TM-score 0.98, RMSD 0.79 Å
- 1GUX chain B against the predicted model P06400: TM-score 0.98, RMSD 0.79 Å
- 4ELJ chain A against the predicted model P06400: TM-score 0.98, RMSD 1.38 Å
- 4ELJ chain A against the predicted model P06400: TM-score 0.98, RMSD 1.38 Å
- 1O9K chain B against the predicted model P06400: TM-score 0.97, RMSD 0.86 Å
- 1O9K chain B against the predicted model P06400: TM-score 0.97, RMSD 0.86 Å
- 4ELL chain A against the predicted model P06400: TM-score 0.97, RMSD 1.32 Å
- 4ELL chain A against the predicted model P06400: TM-score 0.97, RMSD 1.32 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.