UniProt P06243
Cell division control protein 7 (P06243)
Cell division control protein 7 (UniProt P06243), EC 2.7.11.1: 3 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P06243
- Protein
- Cell division control protein 7
- EC
- 2.7.11.1
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 1 · 1 record with a druggable one
Structures
4 records of P06243 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7P5Z | Structure of a DNA-loaded MCM double hexamer engaged with the Dbf4-dependent kinase | electron microscopy | 1 | — | 1 (best 0.84) |
| 7PT7 | Structure of MCM2-7 DH complexed with Cdc7-Dbf4 in the presence of ADP:BeF3, state I | electron microscopy | 8 | ADP, MG, BEF, ZN | — |
| 7V3V | Cryo-EM structure of MCM double hexamer bound with DDK in State I | electron microscopy | H | AGS | — |
| P06243 | AlphaFold monomer V2.0 prediction for cell division control protein 7 (P06243) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7V3V chain H against the predicted model P06243: TM-score 0.96, RMSD 1.59 Å
- 7PT7 chain 8 against the predicted model P06243: TM-score 0.95, RMSD 2.09 Å
- 7P5Z chain 1 against the predicted model P06243: TM-score 0.86, RMSD 2.52 Å
Elsewhere
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