UniProt P06106
Homocysteine/cysteine synthase (P06106)
Homocysteine/cysteine synthase (UniProt P06106), EC 2.5.1.47, 2.5.1.49: 1 experimental structure and 1 predicted model on GenesisL1, 1 ligand bound, 12 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P06106
- Protein
- Homocysteine/cysteine synthase
- EC
- 2.5.1.47, 2.5.1.49
- Experimental structures
- 1
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 12 · 1 record with a druggable one
Structures
2 records of P06106 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8OVH | Crystal structure of O-acetyl-L-homoserine sulfhydrolase from Saccharomyces cerevisiae in complex… | x-ray diffraction | A, B, C, D | PLP | 12 (best 0.80) |
| P06106 | AlphaFold monomer V2.0 prediction for HOMOCYSTEINE/CYSTEINE synthase (P06106) | predicted | A | — | — |
Ligands
- PLP · Pyridoxal-5'-phosphate · in 1 record
Experiment against prediction
- 8OVH chain D against the predicted model P06106: TM-score 0.99, RMSD 0.95 Å
- 8OVH chain A against the predicted model P06106: TM-score 0.99, RMSD 0.71 Å
- 8OVH chain C against the predicted model P06106: TM-score 0.99, RMSD 0.74 Å
- 8OVH chain B against the predicted model P06106: TM-score 0.98, RMSD 1.04 Å
Elsewhere
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