UniProt P05549
Transcription factor AP-2-alpha (P05549)
Transcription factor AP-2-alpha (UniProt P05549): 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P05549
- Protein
- Transcription factor AP-2-alpha
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 11 · 2 records with a druggable one
Structures
3 records of P05549 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8J0K | Crystal structure of human TFAP2A in complex with DNA | x-ray diffraction | A, B | PG3 | 5 (best 0.74) |
| 8J0R | Structure of human TFAP2A in complex with DNA | x-ray diffraction | A, B | PG3 | 6 (best 0.67) |
| P05549 | AlphaFold monomer V2.0 prediction for transcription factor ap-2-alpha (P05549) | predicted | A | — | — |
Ligands
- PG3 · Guanidine-3-propanol · in 2 records
Experiment against prediction
- 8J0R chain B against the predicted model P05549: TM-score 0.94, RMSD 1.71 Å
- 8J0K chain B against the predicted model P05549: TM-score 0.94, RMSD 1.85 Å
- 8J0K chain A against the predicted model P05549: TM-score 0.92, RMSD 2.17 Å
- 8J0R chain A against the predicted model P05549: TM-score 0.92, RMSD 2.20 Å
Elsewhere
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