UniProt P05484
Omega-conotoxin MVIIA (P05484)
Omega-conotoxin MVIIA (UniProt P05484): 18 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P05484
- Protein
- Omega-conotoxin MVIIA
- Experimental structures
- 18
- Predicted models
- 1
- Pockets
- 3 · 2 records with a druggable one
Structures
19 records of P05484 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1DW4 | NMR structure of omega-conotoxin mviia: constraints on disulphide bridges | solution nmr | A | — | — |
| 1DW4 | NMR structure of omega-conotoxin mviia: constraints on disulphide bridges | solution nmr | A | — | — |
| 1DW5 | NMR structure of omega-conotoxin mviia: no constraints on disulphide bridges | solution nmr | A | — | — |
| 1DW5 | NMR structure of omega-conotoxin mviia: no constraints on disulphide bridges | solution nmr | A | — | — |
| 1FEO | Solution structure of omega-conotoxin MVIIA with C-terminal Gly | solution nmr | A | — | — |
| 1FEO | Solution structure of omega-conotoxin mviia with C-terminal gly | solution nmr | A | — | — |
| 1MVI | N-type calcium channel blocker, omega-conotoxin mviia, NMR, 15 structures | solution nmr | A | — | — |
| 1MVI | N-type calcium channel blocker, omega-conotoxin mviia, NMR, 15 structures | solution nmr | A | — | — |
| 1OMG | NMR study of omega-conotoxin mviia | solution nmr | A | — | — |
| 1OMG | NMR study of omega-conotoxin mviia | solution nmr | A | — | — |
| 1TT3 | NMR soulution structure of omega-conotoxin [K10]MVIIA | solution nmr | A | — | — |
| 1TT3 | NMR soulution structure of omega-conotoxin [K10]MVIIA | solution nmr | A | — | — |
| 1TTK | NMR solution structure of omega-conotoxin MVIIA, a N-type calcium channel blocker | solution nmr | A | — | — |
| 1TTK | NMR solution structure of omega-conotoxin mviia, a N-type calcium channel blocker | solution nmr | A | — | — |
| 7MIX | Human N-type voltage-gated calcium channel Cav2.2 in the presence of ziconotide at 3.0 Angstrom… | electron microscopy | B | — | 2 (best 0.83) |
| 7MIX | Human N-type voltage-gated calcium channel CAV2.2 in the presence of ziconotide at 3.0 ångström… | electron microscopy | B | — | — |
| 7VFU | Human N-type voltage gated calcium channel CaV2.2-alpha2/delta1-beta1 complex, bound to ziconotide | electron microscopy | E | — | 1 (best 0.86) |
| 7VFU | Human N-type voltage gated calcium channel CAV2.2-ALPHA2/DELTA1-BETA1 complex, bound to ziconotide | electron microscopy | E | — | — |
| P05484 | AlphaFold monomer V2.0 prediction for omega-conotoxin mviia (P05484) | predicted | A | — | — |
Experiment against prediction
- 7MIX chain B against the predicted model P05484: TM-score 0.76, RMSD 0.54 Å
- 7MIX chain B against the predicted model P05484: TM-score 0.76, RMSD 0.54 Å
- 7VFU chain E against the predicted model P05484: TM-score 0.72, RMSD 0.63 Å
- 7VFU chain E against the predicted model P05484: TM-score 0.72, RMSD 0.63 Å
- 1TT3 chain A against the predicted model P05484: TM-score 0.59, RMSD 0.98 Å
- 1TT3 chain A against the predicted model P05484: TM-score 0.59, RMSD 0.98 Å
- 1MVI chain A against the predicted model P05484: TM-score 0.58, RMSD 1.46 Å
- 1MVI chain A against the predicted model P05484: TM-score 0.58, RMSD 1.46 Å
- 1DW4 chain A against the predicted model P05484: TM-score 0.57, RMSD 1.13 Å
- 1DW4 chain A against the predicted model P05484: TM-score 0.57, RMSD 1.13 Å
Elsewhere
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