UniProt P05095
Myosin-14,Alpha-actinin A (P05095)
Myosin-14,Alpha-actinin A (UniProt P05095): 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P05095
- Protein
- Myosin-14,Alpha-actinin A
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 13 · 1 record with a druggable one
Structures
9 records of P05095 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1G8X | Structure of a genetically engineered molecular motor | x-ray diffraction | A, B | — | — |
| 1G8X | Structure of a genetically engineered molecular motor | x-ray diffraction | A, B | — | — |
| 4PD3 | Crystal Structure of Rigor-Like Human Nonmuscle Myosin-2B | x-ray diffraction | A, B | — | — |
| 4PD3 | Crystal structure of rigor-like human nonmuscle myosin-2B | x-ray diffraction | A, B | — | — |
| 5I4E | Crystal Structure of Human Nonmuscle Myosin 2C motor domain | x-ray diffraction | A | AOV, MG | 13 (best 0.74) |
| 5I4E | Crystal structure of human nonmuscle myosin 2C motor domain | x-ray diffraction | A | — | — |
| 5JLH | Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution | electron microscopy | F, G | — | — |
| 5JLH | Cryo-EM structure of a human cytoplasmic actomyosin complex at near- atomic resolution | electron microscopy | F, G | — | — |
| P05095 | AlphaFold monomer V2.0 prediction for alpha-actinin a (P05095) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1G8X chain A against the predicted model P08799: TM-score 0.67, RMSD 3.57 Å
- 1G8X chain A against the predicted model P08799: TM-score 0.67, RMSD 3.57 Å
- 4PD3 chain B against the predicted model P05095: TM-score 0.31, RMSD 6.34 Å
- 4PD3 chain B against the predicted model P05095: TM-score 0.31, RMSD 6.34 Å
- 5I4E chain A against the predicted model P05095: TM-score 0.29, RMSD 6.11 Å
- 5I4E chain A against the predicted model P05095: TM-score 0.29, RMSD 6.11 Å
- 1G8X chain B against the predicted model P05095: TM-score 0.28, RMSD 5.47 Å
- 1G8X chain B against the predicted model P05095: TM-score 0.28, RMSD 5.47 Å
- 1G8X chain A against the predicted model P05095: TM-score 0.27, RMSD 6.13 Å
- 1G8X chain A against the predicted model P05095: TM-score 0.27, RMSD 6.13 Å
Elsewhere
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