UniProt P05062
Fructose-bisphosphate aldolase B (P05062)
Fructose-bisphosphate aldolase B (UniProt P05062), EC 4.1.2.13: 7 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 80 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P05062
- Protein
- Fructose-bisphosphate aldolase B
- EC
- 4.1.2.13
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 80 · 4 records with a druggable one
Structures
8 records of P05062 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1QO5 | Fructose 1,6-bisphosphate Aldolase from Human Liver Tissue | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R | SO4 | 20 (best 0.89) |
| 1QO5 | Fructose 1,6-bisphosphate aldolase from human liver tissue | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R | — | — |
| 1XDL | Structure of human aldolase B associated with hereditary fructose intolerance (A149P), at 277K | x-ray diffraction | A, B, C, D, W, X, Y, Z | SO4 | 20 (best 0.82) |
| 1XDL | Structure of human aldolase B associated with hereditary fructose intolerance (A149P), at 277K | x-ray diffraction | A, B, C, D, W, X, Y, Z | — | — |
| 1XDM | Structure of human aldolase B associated with hereditary fructose intolerance (A149P), at 291K | x-ray diffraction | A, B, C, D, W, X, Y, Z | SO4 | 20 (best 0.81) |
| 1XDM | Structure of human aldolase B associated with hereditary fructose intolerance (A149P), at 291K | x-ray diffraction | A, B, C, D, W, X, Y, Z | — | — |
| 8D44 | Cryo-electron microscopy structure of human kidney Fructose-bisphosphate aldolase B | electron microscopy | D, C, B, A | — | 20 (best 0.83) |
| P05062 | AlphaFold monomer V2.0 prediction for fructose-bisphosphate aldolase B (P05062) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 3 records
Experiment against prediction
- 1QO5 chain K against the predicted model P05062: TM-score 1.00, RMSD 0.47 Å
- 1QO5 chain K against the predicted model P05062: TM-score 1.00, RMSD 0.47 Å
- 1QO5 chain L against the predicted model P05062: TM-score 0.99, RMSD 0.79 Å
- 1QO5 chain L against the predicted model P05062: TM-score 0.99, RMSD 0.79 Å
- 1QO5 chain O against the predicted model P05062: TM-score 0.99, RMSD 0.79 Å
- 1QO5 chain O against the predicted model P05062: TM-score 0.99, RMSD 0.79 Å
- 1QO5 chain Q against the predicted model P05062: TM-score 0.99, RMSD 0.84 Å
- 1QO5 chain Q against the predicted model P05062: TM-score 0.99, RMSD 0.84 Å
- 1XDL chain Z against the predicted model P05062: TM-score 0.99, RMSD 0.59 Å
- 1XDL chain Z against the predicted model P05062: TM-score 0.99, RMSD 0.59 Å
Elsewhere
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