UniProt P04440
HLA class II histocompatibility antigen, DP beta 1 chain (P04440)
HLA class II histocompatibility antigen, DP beta 1 chain (UniProt P04440): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 14 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P04440
- Protein
- HLA class II histocompatibility antigen, DP beta 1 chain
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 14 · 1 record with a druggable one
Structures
7 records of P04440 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4P4K | Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between allergic hypersensitivity… | x-ray diffraction | B, F | — | — |
| 4P4K | Structural basis of chronic beryllium disease: bridging the gap between allergic hypersensitivity… | x-ray diffraction | B, F | — | — |
| 4P4R | Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergic Hypersensitivity… | x-ray diffraction | B, D | — | — |
| 4P4R | Structural basis of chronic beryllium disease: bridging the gap between allergic hypersensitivity… | x-ray diffraction | B, D | — | — |
| 7T2C | Crystal structure of the B5 TCR in complex with HLA-DP4-Ply | x-ray diffraction | B | NAG | 4 (best 0.47) |
| 7T2D | Crystal structure of the B1 TCR in complex with HLA-DP4-Ply | x-ray diffraction | B, G, L, Q | NAG | 10 (best 0.54) |
| P04440 | AlphaFold monomer V2.0 prediction for HLA class II histocompatibility antigen, dp beta 1 chain… | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
Experiment against prediction
- 7T2D chain Q against the predicted model P04440: TM-score 0.89, RMSD 1.88 Å
- 7T2D chain B against the predicted model P04440: TM-score 0.89, RMSD 1.92 Å
- 7T2D chain L against the predicted model P04440: TM-score 0.89, RMSD 1.94 Å
- 7T2D chain G against the predicted model P04440: TM-score 0.88, RMSD 2.00 Å
- 7T2C chain B against the predicted model P04440: TM-score 0.88, RMSD 1.99 Å
- 4P4R chain D against the predicted model P04440: TM-score 0.82, RMSD 2.08 Å
- 4P4K chain F against the predicted model P04440: TM-score 0.82, RMSD 2.14 Å
- 4P4R chain B against the predicted model P04440: TM-score 0.79, RMSD 2.44 Å
- 4P4R chain B against the predicted model P04440: TM-score 0.79, RMSD 2.44 Å
- 4P4K chain B against the predicted model P04440: TM-score 0.77, RMSD 2.64 Å
Elsewhere
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