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UniProt P04273

Major prion protein (P04273)

Major prion protein (UniProt P04273): 16 experimental structures on GenesisL1, 19 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P04273
Protein
Major prion protein
Experimental structures
16
Predicted models
0
Pockets
19 · 1 record with a druggable one

Structures

16 records of P04273 in the MolNFT archive: 16 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
1B10Solution NMR structure of recombinant syrian hamster prion protein RPRP(90-231) , 25 structuressolution nmrA——
1B10Solution NMR structure of recombinant syrian hamster prion protein RPRP(90-231) , 25 structuressolution nmrA——
2KKGNMR structure of the octarepeat region of prion protein bound to pentosan polysulfatesolution nmrA——
2KKGNMR structure of the octarepeat region of prion protein bound to pentosan polysulfatesolution nmrA——
2LH8Syrian hamster prion protein with thiaminesolution nmrA——
2LH8Syrian hamster prion protein with thiaminesolution nmrA——
3NVEMMHFGN segment 138-143 from Syrian Hamster prionx-ray diffractionA, B——
3NVEMmhfgn segment 138-143 from syrian hamster prionx-ray diffractionA, B——
4YXLCrystal structure of Syrian hamster prion protein complexed with POM1 FABx-ray diffractionA——
4YXLCrystal structure of syrian hamster prion protein complexed with POM1 Fabx-ray diffractionA——
7LNAInfectious mammalian prion fibril (263K scrapie)electron microscopyA, B, C—4 (best 0.48)
7LNAInfectious mammalian prion fibril (263K scrapie)electron microscopyA, B, C——
7YATCryoEM tetra protofilament structure of the hamster prion 108-144 fibrilelectron microscopyA, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, X, Y—12 (best 0.80)
7YATCryoem tetra protofilament structure of the hamster prion 108-144 fibrilelectron microscopyA, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, X, Y——
8WZXCryo-EM structure of the hamster prion 23-144 fibril at pH 3.7electron microscopyA, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T—3 (best 0.46)
P04273AlphaFold monomer V2.0 prediction for major prion protein (P04273)———

Elsewhere

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