UniProt P04224
P04224
P04224 (UniProt P04224): 23 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P04224
- Experimental structures
- 23
- Predicted models
- 1
- Ligands
- 3
Structures
24 records of P04224 in the MolNFT archive: 23 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1FNE | Histocompatibility antigen | x-ray diffraction | A, C | — | — |
| 1FNE | Histocompatibility antigen | x-ray diffraction | A, C | — | — |
| 1FNG | Histocompatibility antigen | x-ray diffraction | A, C | — | — |
| 1FNG | Histocompatibility antigen | x-ray diffraction | A, C | — | — |
| 1I3R | Crystal structure of a mutant iek class II MHC molecule | x-ray diffraction | A, C, E, G | — | — |
| 1I3R | Crystal structure of a mutant iek class II MHC molecule | x-ray diffraction | A, C, E, G | — | — |
| 1R5V | Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to… | x-ray diffraction | A, C | — | — |
| 1R5V | Evidence that structural rearrangements AND/OR flexibility during TCR binding can contribute to… | x-ray diffraction | A, C | — | — |
| 1R5W | Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to… | x-ray diffraction | A, C | — | — |
| 1R5W | Evidence that structural rearrangements AND/OR flexibility during TCR binding can contribute to… | x-ray diffraction | A, C | — | — |
| 3QIB | Crystal structure of the 2B4 TCR in complex with MCC/I-Ek | x-ray diffraction | A | — | — |
| 3QIB | Crystal structure of the 2B4 TCR in complex with MCC/I-ek | x-ray diffraction | A | — | — |
| 3QIU | Crystal structure of the 226 TCR in complex with MCC/I-Ek | x-ray diffraction | A | — | — |
| 3QIU | Crystal structure of the 226 TCR in complex with MCC/I-ek | x-ray diffraction | A | — | — |
| 3QIW | Crystal structure of the 226 TCR in complex with MCC-p5E/I-Ek | x-ray diffraction | A | — | — |
| 3QIW | Crystal structure of the 226 TCR in complex with mcc-P5E/I-ek | x-ray diffraction | A | — | — |
| 4P2O | Crystal structure of the 2B4 TCR in complex with 2A/I-Ek | x-ray diffraction | A | — | — |
| 4P2O | Crystal structure of the 2B4 TCR in complex with 2A/I-ek | x-ray diffraction | A | — | — |
| 4P2Q | Crystal structure of the 5cc7 TCR in complex with 5c2/I-Ek | x-ray diffraction | A, F, K, P | — | — |
| 4P2Q | Crystal structure of the 5CC7 TCR in complex with 5C2/I-ek | x-ray diffraction | A, F, K, P | — | — |
| 4P2R | Crystal structure of the 5cc7 TCR in complex with 5c1/I-Ek | x-ray diffraction | A, F, K, P | — | — |
| 4P2R | Crystal structure of the 5CC7 TCR in complex with 5C1/I-ek | x-ray diffraction | A, F, K, P | — | — |
| 6BGA | 2B4 I-ek TCR-MHC complex with affinity-enhancing velcro peptide | x-ray diffraction | A | NAG, FUC, PO4 | — |
| P04224 | AlphaFold monomer V2.0 prediction for H-2 class II histocompatibility antigen, E-K alpha chain… | predicted | A | — | — |
Ligands
Experiment against prediction
- 3QIU chain A against the predicted model P04224: TM-score 0.97, RMSD 0.91 Å
- 3QIU chain A against the predicted model P04224: TM-score 0.97, RMSD 0.91 Å
- 3QIW chain A against the predicted model P04224: TM-score 0.97, RMSD 0.91 Å
- 3QIW chain A against the predicted model P04224: TM-score 0.97, RMSD 0.91 Å
- 4P2O chain A against the predicted model P04224: TM-score 0.97, RMSD 0.95 Å
- 4P2O chain A against the predicted model P04224: TM-score 0.97, RMSD 0.95 Å
- 1R5W chain A against the predicted model P04224: TM-score 0.97, RMSD 1.04 Å
- 1R5W chain A against the predicted model P04224: TM-score 0.97, RMSD 1.04 Å
- 3QIB chain A against the predicted model P04224: TM-score 0.96, RMSD 1.02 Å
- 3QIB chain A against the predicted model P04224: TM-score 0.96, RMSD 1.02 Å
Elsewhere
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