UniProt P04066
Tissue alpha-L-fucosidase (P04066)
Tissue alpha-L-fucosidase (UniProt P04066), EC 3.2.1.51: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 34 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P04066
- Protein
- Tissue alpha-L-fucosidase
- EC
- 3.2.1.51
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 34 · 2 records with a druggable one
Structures
5 records of P04066 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7PLS | Cryo-EM structures of human fucosidase FucA1 reveal insight into substate recognition and catalysis. | electron microscopy | A, B, C, D | NAG | 18 (best 0.81) |
| 7PLS | Cryo-EM structures of human fucosidase FUCA1 reveal insight into substate recognition and catalysis. | electron microscopy | A, B, C, D | NAG | — |
| 7PM4 | Cryo-EM structures of human fucosidase FucA1 reveal insight into substate recognition and catalysis. | electron microscopy | A, B, C, D | NAG, DFU | 16 (best 0.80) |
| 7PM4 | Cryo-EM structures of human fucosidase FUCA1 reveal insight into substate recognition and catalysis. | electron microscopy | A, B, C, D | NAG, DFU | — |
| P04066 | AlphaFold monomer V2.0 prediction for tissue alpha-L-fucosidase (P04066) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7PLS chain A against the predicted model P04066: TM-score 0.99, RMSD 0.65 Å
- 7PLS chain B against the predicted model P04066: TM-score 0.99, RMSD 0.65 Å
- 7PLS chain C against the predicted model P04066: TM-score 0.99, RMSD 0.65 Å
- 7PLS chain D against the predicted model P04066: TM-score 0.99, RMSD 0.65 Å
- 7PLS chain A against the predicted model P04066: TM-score 0.99, RMSD 0.65 Å
- 7PLS chain B against the predicted model P04066: TM-score 0.99, RMSD 0.65 Å
- 7PLS chain C against the predicted model P04066: TM-score 0.99, RMSD 0.65 Å
- 7PLS chain D against the predicted model P04066: TM-score 0.99, RMSD 0.65 Å
- 7PM4 chain A against the predicted model P04066: TM-score 0.99, RMSD 0.70 Å
- 7PM4 chain B against the predicted model P04066: TM-score 0.99, RMSD 0.70 Å
Elsewhere
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