UniProt P03953
Complement factor D (P03953)
Complement factor D (UniProt P03953), EC 3.4.21.46: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P03953
- Protein
- Complement factor D
- EC
- 3.4.21.46
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
3 records of P03953 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5FCR | Mouse complement factor D | x-ray diffraction | A, B, C, D | SO4 | 3 (best 0.76) |
| 5FCR | Mouse complement factor D | x-ray diffraction | A, B, C, D | — | — |
| P03953 | AlphaFold monomer V2.0 prediction for complement factor D (P03953) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 5FCR chain C against the predicted model P03953: TM-score 1.00, RMSD 0.28 Å
- 5FCR chain C against the predicted model P03953: TM-score 1.00, RMSD 0.28 Å
- 5FCR chain D against the predicted model P03953: TM-score 1.00, RMSD 0.31 Å
- 5FCR chain D against the predicted model P03953: TM-score 1.00, RMSD 0.31 Å
- 5FCR chain A against the predicted model P03953: TM-score 1.00, RMSD 0.35 Å
- 5FCR chain A against the predicted model P03953: TM-score 1.00, RMSD 0.35 Å
- 5FCR chain B against the predicted model P03953: TM-score 1.00, RMSD 0.36 Å
- 5FCR chain B against the predicted model P03953: TM-score 1.00, RMSD 0.36 Å
Elsewhere
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