UniProt P03882
Intron-encoded endonuclease I-scei (P03882)
Intron-encoded endonuclease I-scei (UniProt P03882), EC 3.1.-.-: 12 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P03882
- Protein
- Intron-encoded endonuclease I-scei
- EC
- 3.1.-.-
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 11 · 1 record with a druggable one
Structures
13 records of P03882 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1R7M | The homing endonuclease I-SceI bound to its DNA recognition region | x-ray diffraction | A, B | — | — |
| 1R7M | The homing endonuclease I-scei bound to its DNA recognition region | x-ray diffraction | A, B | — | — |
| 3C0W | I-SceI in complex with a bottom nicked DNA substrate | x-ray diffraction | A | — | — |
| 3C0W | I-scei in complex with a bottom nicked DNA substrate | x-ray diffraction | A | — | — |
| 3C0X | I-SceI in complex with a top nicked DNA substrate | x-ray diffraction | A | — | — |
| 3C0X | I-scei in complex with a top nicked DNA substrate | x-ray diffraction | A | — | — |
| 3OOL | I-SceI complexed with C/G+4 DNA substrate | x-ray diffraction | A | — | — |
| 3OOL | I-scei complexed with C/G+4 DNA substrate | x-ray diffraction | A | — | — |
| 3OOR | I-SceI mutant (K86R/G100T)complexed with C/G+4 DNA substrate | x-ray diffraction | A | — | — |
| 3OOR | I-scei mutant (K86R/G100T)COMPLEXED with C/G+4 DNA substrate | x-ray diffraction | A | — | — |
| 5A0M | The crystal structure of I-scei in complex with its target DNA in the presence of mn | x-ray diffraction | A, B | MN | 10 (best 0.82) |
| 5A0M | The crystal structure of I-scei in complex with its target DNA in the presence of mn | x-ray diffraction | A, B | — | — |
| P03882 | AlphaFold monomer V2.0 prediction for intron-encoded endonuclease I-scei (P03882) | predicted | A | — | 1 (best 0.39) |
Ligands
- MN · Manganese (II) ion · in 1 record
Experiment against prediction
- 5A0M chain B against the predicted model P03882: TM-score 1.00, RMSD 0.32 Å
- 5A0M chain B against the predicted model P03882: TM-score 1.00, RMSD 0.32 Å
- 5A0M chain A against the predicted model P03882: TM-score 0.99, RMSD 0.41 Å
- 5A0M chain A against the predicted model P03882: TM-score 0.99, RMSD 0.41 Å
- 1R7M chain A against the predicted model P03882: TM-score 0.99, RMSD 0.42 Å
- 1R7M chain A against the predicted model P03882: TM-score 0.99, RMSD 0.42 Å
- 3OOR chain A against the predicted model P03882: TM-score 0.99, RMSD 0.48 Å
- 3OOR chain A against the predicted model P03882: TM-score 0.99, RMSD 0.48 Å
- 3OOL chain A against the predicted model P03882: TM-score 0.99, RMSD 0.49 Å
- 3OOL chain A against the predicted model P03882: TM-score 0.99, RMSD 0.49 Å
Elsewhere
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