UniProt P02920
Lactose permease (P02920)
Lactose permease (UniProt P02920): 18 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P02920
- Protein
- Lactose permease
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 4 · 3 records with a druggable one
Structures
19 records of P02920 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PV6 | Crystal structure of lactose permease | x-ray diffraction | A, B | — | — |
| 1PV6 | Crystal structure of lactose permease | x-ray diffraction | A, B | — | — |
| 1PV7 | Crystal structure of lactose permease with TDG | x-ray diffraction | A, B | — | — |
| 1PV7 | Crystal structure of lactose permease with tdg | x-ray diffraction | A, B | — | — |
| 2CFP | Sugar Free Lactose Permease at acidic pH | x-ray diffraction | A | — | — |
| 2CFP | Sugar free lactose permease at acidic pH | x-ray diffraction | A | — | — |
| 2CFQ | Sugar Free Lactose Permease at neutral pH | x-ray diffraction | A | — | — |
| 2CFQ | Sugar free lactose permease at neutral pH | x-ray diffraction | A | — | — |
| 2V8N | Wild-type Structure of Lactose Permease | x-ray diffraction | A, B | — | — |
| 2V8N | Wild-type structure of lactose permease | x-ray diffraction | A, B | — | — |
| 2Y5Y | Crystal structure of LacY in complex with an affinity inactivator | x-ray diffraction | A, B | — | — |
| 2Y5Y | Crystal structure of lacy in complex with an affinity inactivator | x-ray diffraction | A, B | — | — |
| 4ZYR | Crystal structure of E. coli Lactose permease G46W/G262W bound to p-nitrophenyl… | x-ray diffraction | A, B | — | — |
| 4ZYR | Crystal structure of E. COLI lactose permease G46W/G262W bound to P- nitrophenyl… | x-ray diffraction | A, B | — | — |
| 5GXB | crystal structure of a LacY/Nanobody complex | x-ray diffraction | A | — | 1 (best 0.83) |
| 5GXB | Crystal structure of a LACY/NANOBODY complex | x-ray diffraction | A | — | — |
| 6C9W | Crystal Structure of a ligand bound LacY/Nanobody Complex | x-ray diffraction | A | 9PG, BNG | 1 (best 0.87) |
| 6C9W | Crystal structure of a ligand bound LACY/NANOBODY complex | x-ray diffraction | A | 9PG, BNG | — |
| P02920 | AlphaFold monomer V2.0 prediction for lactose permease (P02920) | predicted | A | — | 2 (best 0.85) |
Ligands
Experiment against prediction
- 2Y5Y chain A against the predicted model P02920: TM-score 0.97, RMSD 1.32 Å
- 2Y5Y chain A against the predicted model P02920: TM-score 0.97, RMSD 1.32 Å
- 2Y5Y chain B against the predicted model P02920: TM-score 0.95, RMSD 1.79 Å
- 2Y5Y chain B against the predicted model P02920: TM-score 0.95, RMSD 1.79 Å
- 2CFQ chain A against the predicted model P02920: TM-score 0.93, RMSD 1.65 Å
- 2CFQ chain A against the predicted model P02920: TM-score 0.93, RMSD 1.65 Å
- 2CFP chain A against the predicted model P02920: TM-score 0.93, RMSD 1.66 Å
- 2CFP chain A against the predicted model P02920: TM-score 0.93, RMSD 1.66 Å
- 2V8N chain A against the predicted model P02920: TM-score 0.93, RMSD 1.81 Å
- 2V8N chain A against the predicted model P02920: TM-score 0.93, RMSD 1.81 Å
Elsewhere
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