UniProt P02836
Segmentation polarity homeobox protein engrailed (P02836)
Segmentation polarity homeobox protein engrailed (UniProt P02836): 28 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P02836
- Protein
- Segmentation polarity homeobox protein engrailed
- Experimental structures
- 28
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
29 records of P02836 in the MolNFT archive: 28 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1DU0 | Engrailed homeodomain Q50A variant DNA complex | x-ray diffraction | A, B | — | — |
| 1DU0 | Engrailed homeodomain Q50A variant DNA complex | x-ray diffraction | A, B | — | — |
| 1ENH | Structural studies of the engrailed homeodomain | x-ray diffraction | A | — | — |
| 1ENH | Structural studies of the engrailed homeodomain | x-ray diffraction | A | — | — |
| 1HDD | Crystal structure of an engrailed homeodomain-DNA complex at 2.8 ångströms resolution: a framework… | x-ray diffraction | C, D | — | — |
| 1HDD | Crystal structure of an engrailed homeodomain-DNA complex at 2.8 ångströms resolution: a framework… | x-ray diffraction | C, D | — | — |
| 1P7I | Crystal structure of engrailed homeodomain mutant K52A | x-ray diffraction | A, B, C, D | — | — |
| 1P7I | Crystal structure of engrailed homeodomain mutant K52A | x-ray diffraction | A, B, C, D | — | — |
| 1P7J | Crystal structure of engrailed homeodomain mutant K52E | x-ray diffraction | A, B, C, D | — | — |
| 1P7J | Crystal structure of engrailed homeodomain mutant K52E | x-ray diffraction | A, B, C, D | — | — |
| 1ZTR | Solution structure of Engrailed homeodomain L16A mutant | solution nmr | A | — | — |
| 1ZTR | Solution structure of engrailed homeodomain L16A mutant | solution nmr | A | — | — |
| 2HDD | Engrailed homeodomain Q50K variant DNA complex | x-ray diffraction | A, B | — | — |
| 2HDD | Engrailed homeodomain Q50K variant DNA complex | x-ray diffraction | A, B | — | — |
| 2HOS | Phage-Selected Homeodomain Bound to Unmodified DNA | x-ray diffraction | A, B | — | — |
| 2HOS | Phage-selected homeodomain bound to unmodified DNA | x-ray diffraction | A, B | — | — |
| 2HOT | Phage selected homeodomain bound to modified DNA | x-ray diffraction | A, B | — | — |
| 2HOT | Phage selected homeodomain bound to modified DNA | x-ray diffraction | A, B | — | — |
| 2JWT | Solution structure of Engrailed homeodomain WT | solution nmr | A | — | — |
| 2JWT | Solution structure of engrailed homeodomain wt | solution nmr | A | — | — |
| 2P81 | Engrailed homeodomain helix-turn-helix motif | solution nmr | A | — | — |
| 2P81 | Engrailed homeodomain helix-turn-helix motif | solution nmr | A | — | — |
| 3HDD | Engrailed homeodomain DNA complex | x-ray diffraction | A, B | — | — |
| 3HDD | Engrailed homeodomain DNA complex | x-ray diffraction | A, B | — | — |
| 6FVC | Protein environment affects the water-tryptophan binding mode. Molecular dynamics simulations of… | solution nmr | A | — | — |
| 6FVC | Protein environment affects the water-tryptophan binding mode. molecular dynamics simulations of… | solution nmr | A | — | — |
| 6M3D | X-ray crystal structure of tandemly connected engrailed homeodomains (EHD) with R53A mutations and… | x-ray diffraction | C | NA | 2 (best 0.57) |
| 6M3D | X-ray crystal structure of tandemly connected engrailed homeodomains (ehd) with R53A mutations and… | x-ray diffraction | C | NA | — |
| P02836 | AlphaFold monomer V2.0 prediction for segmentation polarity homeobox protein engrailed (P02836) | predicted | A | — | — |
Ligands
- NA · Sodium ion · in 2 records
Experiment against prediction
- 2HOT chain A against the predicted model P02836: TM-score 0.97, RMSD 0.45 Å
- 2HOT chain A against the predicted model P02836: TM-score 0.97, RMSD 0.45 Å
- 2HOS chain A against the predicted model P02836: TM-score 0.97, RMSD 0.46 Å
- 2HOS chain A against the predicted model P02836: TM-score 0.97, RMSD 0.46 Å
- 1P7I chain C against the predicted model P02836: TM-score 0.97, RMSD 0.48 Å
- 1P7I chain C against the predicted model P02836: TM-score 0.97, RMSD 0.48 Å
- 2HDD chain A against the predicted model P02836: TM-score 0.96, RMSD 0.50 Å
- 2HDD chain A against the predicted model P02836: TM-score 0.96, RMSD 0.50 Å
- 1DU0 chain A against the predicted model P02836: TM-score 0.96, RMSD 0.48 Å
- 1DU0 chain A against the predicted model P02836: TM-score 0.96, RMSD 0.48 Å
Elsewhere
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