UniProt P02776
Platelet factor 4 (P02776)
Platelet factor 4 (UniProt P02776): 20 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P02776
- Protein
- Platelet factor 4
- Experimental structures
- 20
- Predicted models
- 1
Structures
21 records of P02776 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1DN3 | NMR structure of a model hydrophilic amphipathic helical basic peptide | solution nmr | A | — | — |
| 1DN3 | NMR structure of a model hydrophilic amphipathic helical basic peptide | solution nmr | A | — | — |
| 1F9Q | Crystal structure of platelet factor 4 | x-ray diffraction | A, B, C, D | — | — |
| 1F9Q | Crystal structure of platelet factor 4 | x-ray diffraction | A, B, C, D | — | — |
| 1F9R | Crystal structure of platelet factor 4 mutant 1 | x-ray diffraction | A, B, C, D | — | — |
| 1F9R | Crystal structure of platelet factor 4 mutant 1 | x-ray diffraction | A, B, C, D | — | — |
| 1F9S | Crystal structure of platelet factor 4 mutant 2 | x-ray diffraction | A, B, C, D | — | — |
| 1F9S | Crystal structure of platelet factor 4 mutant 2 | x-ray diffraction | A, B, C, D | — | — |
| 1PFM | PF4-M2 chimeric mutant with the first 10 N-terminal residues of R-PF4 replaced by the N-terminal… | solution nmr | A, B, C, D | — | — |
| 1PFM | PF4-M2 chimeric mutant with the first 10 N-terminal residues of R-PF4 replaced by the N-terminal… | solution nmr | A, B, C, D | — | — |
| 1PFN | PF4-M2 chimeric mutant with the first 10 N-terminal residues of R-PF4 replaced by the N-terminal… | solution nmr | A, B, C, D | — | — |
| 1PFN | PF4-M2 chimeric mutant with the first 10 N-terminal residues of R-PF4 replaced by the N-terminal… | solution nmr | A, B, C, D | — | — |
| 1RHP | Crystal structure of recombinant human platelet factor 4 | x-ray diffraction | A, B, C, D | — | — |
| 1RHP | Crystal structure of recombinant human platelet factor 4 | x-ray diffraction | A, B, C, D | — | — |
| 4R9W | Crystal structure of platelet factor 4 complexed with fondaparinux | x-ray diffraction | A, B | — | — |
| 4R9W | Crystal structure of platelet factor 4 complexed with fondaparinux | x-ray diffraction | A, B | — | — |
| 4R9Y | Crystal structure of KKOFab in complex with platelet factor 4 | x-ray diffraction | D, C, B, A | — | — |
| 4R9Y | Crystal structure of kkofab in complex with platelet factor 4 | x-ray diffraction | D, C, B, A | — | — |
| 4RAU | crystal structure of RTOFab in complex with human PF4 | x-ray diffraction | C, F, I, L, O, R, U, X | — | — |
| 4RAU | Crystal structure of rtofab in complex with human PF4 | x-ray diffraction | C, F, I, L, O, R, U, X | — | — |
| P02776 | AlphaFold monomer V2.0 prediction for platelet factor 4 (P02776) | predicted | A | — | — |
Experiment against prediction
- 4R9W chain A against the predicted model P02776: TM-score 0.91, RMSD 0.93 Å
- 4R9W chain A against the predicted model P02776: TM-score 0.91, RMSD 0.93 Å
- 1F9S chain B against the predicted model P02776: TM-score 0.90, RMSD 1.06 Å
- 1F9S chain B against the predicted model P02776: TM-score 0.90, RMSD 1.06 Å
- 1F9Q chain B against the predicted model P02776: TM-score 0.89, RMSD 1.10 Å
- 1F9Q chain B against the predicted model P02776: TM-score 0.89, RMSD 1.10 Å
- 1F9R chain B against the predicted model P02776: TM-score 0.89, RMSD 1.12 Å
- 1F9R chain B against the predicted model P02776: TM-score 0.89, RMSD 1.12 Å
- 1RHP chain A against the predicted model P02776: TM-score 0.89, RMSD 1.15 Å
- 1RHP chain A against the predicted model P02776: TM-score 0.89, RMSD 1.15 Å
Elsewhere
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