UniProt P02709
Acetylcholine receptor subunit alpha (P02709)
Acetylcholine receptor subunit alpha (UniProt P02709): 3 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 52 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P02709
- Protein
- Acetylcholine receptor subunit alpha
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 52 · 3 records with a druggable one
Structures
4 records of P02709 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 9AVU | Bovine fetal muscle nAChR bound to ACh | electron microscopy | A, C | NAG, BMA, MAN, POV, ACH | 16 (best 0.85) |
| 9AVV | Bovine adult muscle nAChR resting state | electron microscopy | A, C | NAG, BMA, MAN, POV | 18 (best 0.77) |
| 9AWJ | Bovine adult muscle nAChR bound to ACh | electron microscopy | A, C | NAG, BMA, MAN, ACH, POV | 18 (best 0.83) |
| P02709 | AlphaFold monomer V2.0 prediction for acetylcholine receptor subunit alpha (P02709) | predicted | A | — | — |
Ligands
Experiment against prediction
- 9AVU chain A against the predicted model P02709: TM-score 0.98, RMSD 1.23 Å
- 9AWJ chain A against the predicted model P02709: TM-score 0.97, RMSD 1.25 Å
- 9AWJ chain C against the predicted model P02709: TM-score 0.97, RMSD 1.36 Å
- 9AVU chain C against the predicted model P02709: TM-score 0.97, RMSD 1.36 Å
- 9AVV chain C against the predicted model P02709: TM-score 0.96, RMSD 1.61 Å
- 9AVV chain A against the predicted model P02709: TM-score 0.96, RMSD 1.70 Å
Elsewhere
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