UniProt P02612
Myosin regulatory light chain 2, smooth muscle major isoform (P02612)
Myosin regulatory light chain 2, smooth muscle major isoform (UniProt P02612): 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 7 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P02612
- Protein
- Myosin regulatory light chain 2, smooth muscle major isoform
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 7 · 2 records with a druggable one
Structures
6 records of P02612 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3J04 | EM structure of the heavy meromyosin subfragment of Chick smooth muscle Myosin with regulatory… | electron microscopy | B, E | — | — |
| 3J04 | EM structure of the heavy meromyosin subfragment of chick smooth muscle myosin with regulatory… | electron microscopy | B, E | — | — |
| 7MF3 | Structure of the autoinhibited state of smooth muscle myosin-2 | electron microscopy | D, E | MG | 3 (best 0.90) |
| 7MF3 | Structure of the autoinhibited state of smooth muscle myosin-2 | electron microscopy | D, E | MG | — |
| 8SYF | Homology model of Acto-HMM complex in ADP-state. Chicken smooth muscle HMM and chicken pectoralis… | electron microscopy | F, G | — | 4 (best 0.72) |
| P02612 | AlphaFold monomer V2.0 prediction for myosin regulatory light chain 2, smooth muscle major isoform… | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 2 records
Experiment against prediction
- 3J04 chain B against the predicted model P02612: TM-score 0.80, RMSD 2.43 Å
- 3J04 chain B against the predicted model P02612: TM-score 0.80, RMSD 2.43 Å
- 7MF3 chain E against the predicted model P02612: TM-score 0.64, RMSD 3.84 Å
- 7MF3 chain E against the predicted model P02612: TM-score 0.64, RMSD 3.84 Å
- 8SYF chain F against the predicted model P02612: TM-score 0.63, RMSD 3.79 Å
- 7MF3 chain D against the predicted model P02612: TM-score 0.62, RMSD 4.10 Å
- 7MF3 chain D against the predicted model P02612: TM-score 0.62, RMSD 4.10 Å
- 8SYF chain G against the predicted model P02612: TM-score 0.56, RMSD 4.22 Å
Elsewhere
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