UniProt P02592
Aequorin-2 (P02592)
Aequorin-2 (UniProt P02592): 16 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 60 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P02592
- Protein
- Aequorin-2
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 60 · 3 records with a druggable one
Structures
17 records of P02592 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1EJ3 | Crystal structure of aequorin | x-ray diffraction | A, B | — | — |
| 1EJ3 | Crystal structure of aequorin | x-ray diffraction | A, B | — | — |
| 1UHH | Crystal structure of cp-aequorin | x-ray diffraction | A, B | — | — |
| 1UHH | Crystal structure of cp-aequorin | x-ray diffraction | A, B | — | — |
| 1UHI | Crystal structure of i-aequorin | x-ray diffraction | A, B | — | — |
| 1UHI | Crystal structure of I-aequorin | x-ray diffraction | A, B | — | — |
| 1UHJ | Crystal structure of br-aequorin | x-ray diffraction | A, B | — | — |
| 1UHJ | Crystal structure of br-aequorin | x-ray diffraction | A, B | — | — |
| 1UHK | Crystal structure of n-aequorin | x-ray diffraction | A, B | — | — |
| 1UHK | Crystal structure of N-aequorin | x-ray diffraction | A, B | — | — |
| 5ZAB | Crystal structure of cf3-aequorin | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | 9A3 | 20 (best 0.85) |
| 5ZAB | Crystal structure of CF3-aequorin | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | 9A3 | — |
| 7EG2 | Crystal structure of the apoAequorin complex with (S)-daCTZ | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | J2X | 20 (best 0.85) |
| 7EG2 | Crystal structure of the apoaequorin complex with (S)-dactz | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | J2X | — |
| 7EG3 | Crystal structure of the apoAequorin complex with (S)-HM-daCTZ | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | J2U | 20 (best 0.85) |
| 7EG3 | Crystal structure of the apoaequorin complex with (S)-hm-dactz | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | J2U | — |
| P02592 | AlphaFold monomer V2.0 prediction for aequorin-2 (P02592) | predicted | A | — | — |
Ligands
- 9A3 · (2S)-8-benzyl-2-hydroperoxy-6-(4-hydroxyphenyl)-2-{[4-(trifluoromethyl)phenyl]methyl}imidazo[1,2-a]pyrazin-3(2H)-one · in 2 records
- J2U · (2~{S})-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl) methyl]-4-(phenylmethyl)-2,3-dihydroinden-1-one · in 2 records
- J2X · (2~{S})-2-(hydroxymethyl)-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-4-(phenylmethyl)-3~{H}-inden-1-one · in 2 records
Experiment against prediction
- 1UHI chain B against the predicted model P02592: TM-score 0.97, RMSD 1.03 Å
- 1UHI chain B against the predicted model P02592: TM-score 0.97, RMSD 1.03 Å
- 1UHJ chain A against the predicted model P02592: TM-score 0.96, RMSD 1.04 Å
- 1UHJ chain A against the predicted model P02592: TM-score 0.96, RMSD 1.04 Å
- 1UHH chain B against the predicted model P02592: TM-score 0.96, RMSD 1.05 Å
- 1UHH chain B against the predicted model P02592: TM-score 0.96, RMSD 1.05 Å
- 5ZAB chain P against the predicted model P02592: TM-score 0.96, RMSD 1.06 Å
- 5ZAB chain P against the predicted model P02592: TM-score 0.96, RMSD 1.06 Å
- 5ZAB chain L against the predicted model P02592: TM-score 0.96, RMSD 1.07 Å
- 5ZAB chain L against the predicted model P02592: TM-score 0.96, RMSD 1.07 Å
Elsewhere
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