UniProt P02458
Collagen alpha-1(II) chain (P02458)
Collagen alpha-1(II) chain (UniProt P02458): 11 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P02458
- Protein
- Collagen alpha-1(II) chain
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 2 · 0 records with a druggable one
Structures
12 records of P02458 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1U5M | Structure of a Chordin-like Cysteine-rich Repeat (VWC module) from Collagen IIA | solution nmr | A | — | — |
| 1U5M | Structure of a chordin-like cysteine-rich repeat (vwc module) from collagen iia | solution nmr | A | — | — |
| 2FSE | Crystallographic structure of a rheumatoid arthritis MHC susceptibility allele, HLA-DR1… | x-ray diffraction | E, F | — | — |
| 2FSE | Crystallographic structure of a rheumatoid arthritis MHC susceptibility allele, HLA-DR1… | x-ray diffraction | E, F | — | — |
| 2SEB | X-ray crystal structure of HLA-DR4 complexed with a peptide from human collagen II | x-ray diffraction | E | — | — |
| 2SEB | X-ray crystal structure of HLA-DR4 complexed with a peptide from human collagen II | x-ray diffraction | E | — | — |
| 5NIR | Crystal structure of collagen 2A vWC domain | x-ray diffraction | A, B | — | 2 (best 0.36) |
| 5NIR | Crystal structure of collagen 2A vwc domain | x-ray diffraction | A, B | — | — |
| 6HG7 | Crystal structure of a collagen II fragment containing the binding site of PEDF and COMP… | x-ray diffraction | A, B, C | SO4 | — |
| 6HG7 | Crystal structure of a collagen II fragment containing the binding site of pedf and comp… | x-ray diffraction | A, B, C | ACE, NH2, SO4 | — |
| 7NZE | Crystal structure of HLA-DR4 in complex with a human collagen type II peptide | x-ray diffraction | EEE, FFF | — | — |
| P02458 | AlphaFold monomer V2.0 prediction for collagen alpha-1(II) chain (P02458) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5NIR chain B against the predicted model P02458: TM-score 0.76, RMSD 1.94 Å
- 5NIR chain B against the predicted model P02458: TM-score 0.76, RMSD 1.94 Å
- 5NIR chain A against the predicted model P02458: TM-score 0.75, RMSD 1.70 Å
- 5NIR chain A against the predicted model P02458: TM-score 0.75, RMSD 1.70 Å
- 1U5M chain A against the predicted model P02458: TM-score 0.49, RMSD 1.89 Å
- 1U5M chain A against the predicted model P02458: TM-score 0.49, RMSD 1.89 Å
- 2SEB chain E against the predicted model P02458: TM-score 0.40, RMSD 1.30 Å
- 2SEB chain E against the predicted model P02458: TM-score 0.40, RMSD 1.30 Å
- 2FSE chain E against the predicted model P02458: TM-score 0.36, RMSD 1.13 Å
- 2FSE chain E against the predicted model P02458: TM-score 0.36, RMSD 1.13 Å
Elsewhere
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