UniProt P02302
Histone H3.3C (P02302)
Histone H3.3C (UniProt P02302): 17 experimental structures and 1 predicted model on GenesisL1, 29 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P02302
- Protein
- Histone H3.3C
- Experimental structures
- 17
- Predicted models
- 1
- Pockets
- 29 · 3 records with a druggable one
Structures
18 records of P02302 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AOI | Complex between nucleosome core particle (H3,H4,H2A,H2B) and 146 bp long DNA fragment | x-ray diffraction | A, E | — | — |
| 1AOI | Complex between nucleosome core particle (H3,H4,H2A,H2B) and 146 bp long DNA fragment | x-ray diffraction | A, E | — | — |
| 1M18 | Ligand binding alters the structure and dynamics of nucleosomal DNA | x-ray diffraction | A, E | — | — |
| 1M18 | Ligand binding alters the structure and dynamics of nucleosomal DNA | x-ray diffraction | A, E | — | — |
| 1M19 | Ligand binding alters the structure and dynamics of nucleosomal DNA | x-ray diffraction | A, E | — | — |
| 1M19 | Ligand binding alters the structure and dynamics of nucleosomal DNA | x-ray diffraction | A, E | — | — |
| 1M1A | Ligand binding alters the structure and dynamics of nucleosomal DNA | x-ray diffraction | A, E | — | — |
| 1M1A | Ligand binding alters the structure and dynamics of nucleosomal DNA | x-ray diffraction | A, E | — | — |
| 3C1B | The effect of H3 K79 dimethylation and H4 K20 trimethylation on nucleosome and chromatin structure | x-ray diffraction | A, E | — | — |
| 3C1B | The effect of H3 K79 dimethylation and H4 K20 trimethylation on nucleosome and chromatin structure | x-ray diffraction | A, E | — | — |
| 3C1C | The effect of H3 K79 dimethylation and H4 K20 trimethylation on nucleosome and chromatin structure | x-ray diffraction | A, E | — | — |
| 3C1C | The effect of H3 K79 dimethylation and H4 K20 trimethylation on nucleosome and chromatin structure | x-ray diffraction | A, E | — | — |
| 6FQ8 | Class 3 : translocated nucleosome | electron microscopy | A, E | — | 15 (best 0.85) |
| 6FQ8 | Class 3 : translocated nucleosome | electron microscopy | A, E | — | — |
| 6FTX | Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome | electron microscopy | E | — | 4 (best 0.81) |
| 6FTX | Structure of the chromatin remodelling enzyme CHD1 bound to a ubiquitinylated nucleosome | electron microscopy | E | — | — |
| 8U5H | Cryo-EM structure of human DNMT3A UDR bound to H2AK119ub1-modified nucleosome | electron microscopy | I, O | — | 10 (best 0.82) |
| P02302 | AlphaFold monomer V2.0 prediction for histone H3.3C (P02302) | predicted | A | — | — |
Experiment against prediction
- 1M1A chain A against the predicted model P02302: TM-score 0.99, RMSD 0.44 Å
- 1M1A chain A against the predicted model P02302: TM-score 0.99, RMSD 0.44 Å
- 3C1C chain E against the predicted model P02302: TM-score 0.99, RMSD 0.41 Å
- 3C1C chain E against the predicted model P02302: TM-score 0.99, RMSD 0.41 Å
- 1M19 chain E against the predicted model P02302: TM-score 0.99, RMSD 0.53 Å
- 1M19 chain E against the predicted model P02302: TM-score 0.99, RMSD 0.53 Å
- 1M1A chain E against the predicted model P02302: TM-score 0.99, RMSD 0.65 Å
- 1M1A chain E against the predicted model P02302: TM-score 0.99, RMSD 0.65 Å
- 1M18 chain A against the predicted model P02302: TM-score 0.99, RMSD 0.55 Å
- 1M18 chain A against the predicted model P02302: TM-score 0.99, RMSD 0.55 Å
Elsewhere
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