UniProt P02294
Histone H2B.2 (P02294)
Histone H2B.2 (UniProt P02294): 11 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 86 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P02294
- Protein
- Histone H2B.2
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 86 · 11 records with a druggable one
Structures
12 records of P02294 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ID3 | Crystal structure of the yeast nucleosome core particle reveals fundamental differences in… | x-ray diffraction | D, H | MN | 10 (best 0.78) |
| 1ID3 | Crystal structure of the yeast nucleosome core particle reveals fundamental differences in… | x-ray diffraction | D, H | MN | 10 (best 0.78) |
| 4JJN | Crystal structure of heterochromatin protein Sir3 in complex with a silenced yeast nucleosome | x-ray diffraction | D, H | — | 12 (best 0.78) |
| 4JJN | Crystal structure of heterochromatin protein SIR3 in complex with a silenced yeast nucleosome | x-ray diffraction | D, H | — | 12 (best 0.78) |
| 6QLD | Structure of inner kinetochore CCAN-Cenp-A complex | electron microscopy | d | — | 2 (best 0.79) |
| 6QLD | Structure of inner kinetochore ccan-cenp-a complex | electron microscopy | d | — | 2 (best 0.79) |
| 7E9C | Cryo-EM structure of the 1:1 Orc1 BAH domain in complex with nucleosome | electron microscopy | D, H | — | 11 (best 0.83) |
| 7E9F | Cryo-EM structure of the 2:1 Orc1 BAH domain in complex with nucleosome | electron microscopy | D, H | — | 14 (best 0.80) |
| 8F0X | Cryo-EM structure of Kap114 bound to H2A-H2B | electron microscopy | C | — | 5 (best 0.75) |
| 8F1E | Cryo-EM structure of Kap114 bound to Gsp1 (RanGTP) and H2A-H2B | electron microscopy | C | — | 7 (best 0.75) |
| 8XGC | Structure of yeast replisome associated with FACT and histone hexamer, Composite map | electron microscopy | Q | — | 1 (best 0.81) |
| P02294 | AlphaFold monomer V2.0 prediction for histone H2B.2 (P02294) | predicted | A | — | — |
Ligands
- MN · Manganese (II) ion · in 2 records
Experiment against prediction
- 4JJN chain H against the predicted model P02294: TM-score 0.99, RMSD 0.43 Å
- 4JJN chain H against the predicted model P02294: TM-score 0.99, RMSD 0.43 Å
- 1ID3 chain D against the predicted model P02294: TM-score 0.98, RMSD 0.51 Å
- 1ID3 chain D against the predicted model P02294: TM-score 0.98, RMSD 0.51 Å
- 4JJN chain D against the predicted model P02294: TM-score 0.98, RMSD 0.57 Å
- 4JJN chain D against the predicted model P02294: TM-score 0.98, RMSD 0.57 Å
- 7E9F chain D against the predicted model P02294: TM-score 0.97, RMSD 0.65 Å
- 7E9F chain H against the predicted model P02294: TM-score 0.97, RMSD 0.68 Å
- 8F0X chain C against the predicted model P02294: TM-score 0.96, RMSD 0.78 Å
- 1ID3 chain H against the predicted model P02294: TM-score 0.96, RMSD 0.66 Å
Elsewhere
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