UniProt P02283
Histone H2B (P02283)
Histone H2B (UniProt P02283): 21 experimental structures and 1 predicted model on GenesisL1, 51 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P02283
- Protein
- Histone H2B
- Experimental structures
- 21
- Predicted models
- 1
- Pockets
- 51 · 6 records with a druggable one
Structures
22 records of P02283 in the MolNFT archive: 21 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2NQB | Drosophila Nucleosome Structure | x-ray diffraction | D, H | — | — |
| 2NQB | Drosophila nucleosome structure | x-ray diffraction | D, H | — | — |
| 2PYO | Drosophila nucleosome core | x-ray diffraction | D, H | — | — |
| 2PYO | Drosophila nucleosome core | x-ray diffraction | D, H | — | — |
| 4QLC | Crystal structure of chromatosome at 3.5 angstrom resolution | x-ray diffraction | D, H | — | — |
| 4QLC | Crystal structure of chromatosome at 3.5 ångström resolution | x-ray diffraction | D, H | — | — |
| 4X23 | Crystal structure of cenp-C in complex with the nucleosome core particle | x-ray diffraction | D, H, N, R | — | — |
| 4X23 | Crystal structure of cenp-C in complex with the nucleosome core particle | x-ray diffraction | D, H, N, R | — | — |
| 5CVE | Crystal Structure of human NRMT1 in complex with dimethylated fly H2B peptide and SAH | x-ray diffraction | D, E | — | — |
| 5CVE | Crystal structure of human NRMT1 in complex with dimethylated fly H2B peptide and sah | x-ray diffraction | D, E | — | — |
| 5WCU | Crystal structure of 167 bp nucleosome bound to the globular domain of linker histone H5 | x-ray diffraction | D, H, N, R | — | 12 (best 0.82) |
| 5WCU | Crystal structure of 167 bp nucleosome bound to the globular domain of linker histone H5 | x-ray diffraction | D, H, N, R | — | — |
| 6DZT | Cryo-EM structure of nucleosome in complex with a single chain antibody fragment | electron microscopy | D, H | — | — |
| 6PWE | Cryo-EM structure of nucleosome core particle | electron microscopy | D, H | — | 9 (best 0.79) |
| 6PWE | Cryo-EM structure of nucleosome core particle | electron microscopy | D, H | — | — |
| 6PWF | Cryo-EM structure of the ATPase domain of chromatin remodeling factor ISWI bound to the nucleosome | electron microscopy | D, H | — | 8 (best 0.79) |
| 6PWF | Cryo-EM structure of the ATPase domain of chromatin remodeling factor iswi bound to the nucleosome | electron microscopy | D, H | — | — |
| 7PJ1 | Solution structure of isolated Drosophila histone H2A-H2B heterodimer | solution nmr | B | — | 2 (best 0.71) |
| 7PJ1 | Solution structure of isolated drosophila histone H2A-H2B heterodimer | solution nmr | B | — | — |
| 7XYG | Cryo-EM structure of Fft3-nucleosome complex with Fft3 bound to SHL+3 position of the nucleosome | electron microscopy | D, H | — | 11 (best 0.80) |
| 8PP6 | human RYBP-PRC1 bound to H2AK118ub1 nucleosome | electron microscopy | D, H | — | 9 (best 0.78) |
| P02283 | AlphaFold monomer V2.0 prediction for histone H2B (P02283) | predicted | A | — | — |
Experiment against prediction
- 4X23 chain R against the predicted model P02283: TM-score 0.93, RMSD 1.17 Å
- 4X23 chain R against the predicted model P02283: TM-score 0.93, RMSD 1.17 Å
- 2NQB chain H against the predicted model P02283: TM-score 0.92, RMSD 1.28 Å
- 2NQB chain H against the predicted model P02283: TM-score 0.92, RMSD 1.28 Å
- 4X23 chain D against the predicted model P02283: TM-score 0.92, RMSD 1.20 Å
- 4X23 chain D against the predicted model P02283: TM-score 0.92, RMSD 1.20 Å
- 6DZT chain D against the predicted model P02283: TM-score 0.91, RMSD 1.33 Å
- 4QLC chain D against the predicted model P02283: TM-score 0.91, RMSD 1.31 Å
- 4QLC chain D against the predicted model P02283: TM-score 0.91, RMSD 1.31 Å
- 2NQB chain D against the predicted model P02283: TM-score 0.91, RMSD 1.44 Å
Elsewhere
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