UniProt P01865
Processed angiotensin-converting enzyme 2,Ig gamma-2A chain C region, membrane-bound form (P01865)
Processed angiotensin-converting enzyme 2,Ig gamma-2A chain C region, membrane-bound form (UniProt P01865): 58 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 13 pockets. Binding sites, druggability…
- UniProt
- P01865
- Protein
- Processed angiotensin-converting enzyme 2,Ig gamma-2A chain C region…
- Experimental structures
- 58
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 13 · 1 record with a druggable one
Structures
59 records of P01865 in the MolNFT archive: 58 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AXT | Immune versus natural selection: antibody aldolases with the rates of natural enzymes | x-ray diffraction | H | — | — |
| 1AXT | Immune versus natural selection: antibody aldolases with the rates of natural enzymes | x-ray diffraction | H | — | — |
| 1EGJ | Domain 4 of the beta common chain in complex with an antibody | x-ray diffraction | H | — | — |
| 1EGJ | Domain 4 of the beta common chain in complex with an antibody | x-ray diffraction | H | — | — |
| 1FLR | 4-4-20 Fab fragment | x-ray diffraction | H | — | — |
| 1FLR | 4-4-20 Fab fragment | x-ray diffraction | H | — | — |
| 1FPT | Three-dimensional structure of the complex between the Fab fragment of an neutralizing antibody for… | x-ray diffraction | H | — | — |
| 1FPT | Three-dimensional structure of the complex between the Fab fragment of an neutralizing antibody for… | x-ray diffraction | H | — | — |
| 1GGB | Major antigen-induced domain rearrangements in an antibody | x-ray diffraction | H | — | — |
| 1GGB | Major antigen-induced domain rearrangements in an antibody | x-ray diffraction | H | — | — |
| 1GGC | Major antigen-induced domain rearrangements in an antibody | x-ray diffraction | H | — | — |
| 1GGC | Major antigen-induced domain rearrangements in an antibody | x-ray diffraction | H | — | — |
| 1KB5 | Murine T-cell receptor variable DOMAIN/FAB complex | x-ray diffraction | H | — | — |
| 1KB5 | Murine T-cell receptor variable DOMAIN/FAB complex | x-ray diffraction | H | — | — |
| 1LO0 | Catalytic Retro-Diels-Alderase Transition State Analogue Complex | x-ray diffraction | Y, H | — | — |
| 1LO0 | Catalytic retro-diels-alderase transition state analogue complex | x-ray diffraction | Y, H | — | — |
| 1NBY | Crystal Structure of HyHEL-63 complexed with HEL mutant K96A | x-ray diffraction | B | — | — |
| 1NBY | Crystal structure of hyhel-63 complexed with hel mutant K96A | x-ray diffraction | B | — | — |
| 1NBZ | Crystal Structure of HyHEL-63 complexed with HEL mutant K97A | x-ray diffraction | B | — | — |
| 1NBZ | Crystal structure of hyhel-63 complexed with hel mutant K97A | x-ray diffraction | B | — | — |
| 1NCA | Refined crystal structure of the influenza virus N9 neuraminidase-NC41 Fab complex | x-ray diffraction | H | — | — |
| 1NCA | Refined crystal structure of the influenza virus N9 neuraminidase-NC41 Fab complex | x-ray diffraction | H | — | — |
| 1NCB | Crystal structures of two mutant neuraminidase-antibody complexes with amino acid substitutions in… | x-ray diffraction | H | — | — |
| 1NCB | Crystal structures of two mutant neuraminidase-antibody complexes with amino acid substitutions in… | x-ray diffraction | H | — | — |
| 1NCC | Crystal structures of two mutant neuraminidase-antibody complexes with amino acid substitutions in… | x-ray diffraction | H | — | — |
| 1NCC | Crystal structures of two mutant neuraminidase-antibody complexes with amino acid substitutions in… | x-ray diffraction | H | — | — |
| 1NCD | Refined crystal structure of the influenza virus N9 neuraminidase-NC41 Fab complex | x-ray diffraction | H | — | — |
| 1NCD | Refined crystal structure of the influenza virus N9 neuraminidase-NC41 Fab complex | x-ray diffraction | H | — | — |
| 1ND0 | Cationic cyclization antibody 4C6 complex with transition state analog | x-ray diffraction | B, D, F, H | — | — |
| 1ND0 | Cationic cyclization antibody 4C6 complex with transition state analog | x-ray diffraction | B, D, F, H | — | — |
| 1NDG | Crystal structure of Fab fragment of antibody HyHEL-8 complexed with its antigen lysozyme | x-ray diffraction | B | — | — |
| 1NDG | Crystal structure of Fab fragment of antibody hyhel-8 complexed with its antigen lysozyme | x-ray diffraction | B | — | — |
| 1NDM | Crystal structure of Fab fragment of antibody HyHEL-26 complexed with lysozyme | x-ray diffraction | B | — | — |
| 1NDM | Crystal structure of Fab fragment of antibody hyhel-26 complexed with lysozyme | x-ray diffraction | B | — | — |
| 1ORQ | X-ray structure of a voltage-dependent potassium channel in complex with an Fab | x-ray diffraction | B | — | — |
| 1ORQ | X-ray structure of a voltage-dependent potassium channel in complex with an Fab | x-ray diffraction | B | — | — |
| 1PLG | Evidence for the extended helical nature of polysaccharide epitopes. the 2.8 ångströms resolution… | x-ray diffraction | H | — | — |
| 1PLG | Evidence for the extended helical nature of polysaccharide epitopes. the 2.8 ångströms resolution… | x-ray diffraction | H | — | — |
| 1RU9 | Crystal Structure (A) of u.v.-irradiated cationic cyclization antibody 4C6 Fab at pH 4.6 with a… | x-ray diffraction | H | — | — |
| 1RU9 | Crystal structure (a) of U.V.-irradiated cationic cyclization antibody 4C6 Fab at pH 4.6 with a… | x-ray diffraction | H | — | — |
| 1RUA | Crystal structure (B) of u.v.-irradiated cationic cyclization antibody 4C6 fab at pH 4.6 with a… | x-ray diffraction | H | — | — |
| 1RUA | Crystal structure (B) of U.V.-irradiated cationic cyclization antibody 4C6 Fab at pH 4.6 with a… | x-ray diffraction | H | — | — |
| 1RUK | Crystal structure (C) of native cationic cyclization antibody 4C6 fab at pH 4.6 with a data set… | x-ray diffraction | H | — | — |
| 1RUK | Crystal structure (C) of native cationic cyclization antibody 4C6 Fab at pH 4.6 with a data set… | x-ray diffraction | H | — | — |
| 1RUL | Crystal Structure (D) of u.v.-irradiated cationic cyclization antibody 4C6 Fab at pH 5.6 with a… | x-ray diffraction | H | — | — |
| 1RUL | Crystal structure (D) of U.V.-irradiated cationic cyclization antibody 4C6 Fab at pH 5.6 with a… | x-ray diffraction | H | — | — |
| 1RUM | Crystal structure (F) of H2O2-soaked cationic cyclization antibody 4C6 fab at pH 8.5 with a data… | x-ray diffraction | H | — | — |
| 1RUM | Crystal structure (F) of H2O2-soaked cationic cyclization antibody 4C6 Fab at pH 8.5 with a data… | x-ray diffraction | H | — | — |
| 1RUP | Crystal structure (G) of native cationic cyclization antibody 4C6 fab at pH 8.5 with a data set… | x-ray diffraction | H | — | — |
| 1RUP | Crystal structure (G) of native cationic cyclization antibody 4C6 Fab at pH 8.5 with a data set… | x-ray diffraction | H | — | — |
| 1YEE | Structure of a catalytic antibody, IGG2A Fab fragment (D2.5) | x-ray diffraction | H | — | — |
| 1YEE | Structure of a catalytic antibody, IGG2A Fab fragment (D2.5) | x-ray diffraction | H | — | — |
| 4FAB | Three-dimensional structure of a fluorescein-Fab complex crystallized in 2-methyl-2,4-pentanediol | x-ray diffraction | H | — | — |
| 4FAB | Three-dimensional structure of a fluorescein-Fab complex crystallized in 2-methyl-2,4-pentanediol | x-ray diffraction | H | — | — |
| 4ZXB | Structure of the human insulin receptor ectodomain, irdeltabeta construct, in complex with four Fab… | x-ray diffraction | C | — | — |
| 6UQC | Mouse IGG2A bispecific Fc | x-ray diffraction | C, D, E, F | NAG, BMA, MAN, FUC | — |
| 8AQT | Beta SARS-CoV-2 Spike bound to mouse ACE2 (local) | electron microscopy | A | NAG | 13 (best 0.89) |
| 8AQV | BA.2.12.1 SARS-CoV-2 Spike bound to mouse ACE2 (local) | electron microscopy | A | NAG | — |
| P01865 | AlphaFold monomer V2.0 prediction for ig gamma-2A chain C region, membrane-bound form (P01865) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8AQV chain A against the predicted model Q8R0I0: TM-score 0.98, RMSD 1.10 Å
- 6UQC chain E against the predicted model P01865: TM-score 0.96, RMSD 1.07 Å
- 6UQC chain F against the predicted model P01865: TM-score 0.96, RMSD 1.13 Å
- 6UQC chain C against the predicted model P01865: TM-score 0.96, RMSD 1.26 Å
- 6UQC chain D against the predicted model P01865: TM-score 0.95, RMSD 1.37 Å
- 8AQT chain A against the predicted model Q8R0I0: TM-score 0.86, RMSD 3.53 Å
- 1ND0 chain H against the predicted model P01865: TM-score 0.52, RMSD 4.36 Å
- 1ND0 chain H against the predicted model P01865: TM-score 0.52, RMSD 4.36 Å
- 1ND0 chain D against the predicted model P01865: TM-score 0.52, RMSD 4.09 Å
- 1ND0 chain D against the predicted model P01865: TM-score 0.52, RMSD 4.09 Å
Elsewhere
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