UniProt P01583
Interleukin-1 alpha (P01583)
Interleukin-1 alpha (UniProt P01583): 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P01583
- Protein
- Interleukin-1 alpha
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
Structures
9 records of P01583 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2ILA | Structure of interleukin 1ALPHA at 2.7-ångströms resolution | x-ray diffraction | A | — | — |
| 2ILA | Structure of interleukin 1ALPHA at 2.7-ångströms resolution | x-ray diffraction | A | — | — |
| 2KKI | Solution structure of human Interleukin 1a | solution nmr | A | — | — |
| 2KKI | Solution structure of human interleukin 1A | solution nmr | A | — | — |
| 2L5X | Solution structure of IL1A-S100A13 complex | solution nmr | A, D | — | — |
| 2L5X | Solution structure of IL1A-S100A13 complex | solution nmr | A, D | — | — |
| 5UC6 | Structural insights into IL-1 alpha recognition by a naphthyl-modified aptamer that mimics IL-1RI… | x-ray diffraction | A | MG, NA | — |
| 5UC6 | Structural insights into il-1 alpha recognition by a naphthyl-modified aptamer that mimics il-1RI… | x-ray diffraction | A | MG, NA | — |
| P01583 | AlphaFold monomer V2.0 prediction for interleukin-1 alpha (P01583) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2ILA chain A against the predicted model P01583: TM-score 0.99, RMSD 0.39 Å
- 2ILA chain A against the predicted model P01583: TM-score 0.99, RMSD 0.39 Å
- 5UC6 chain A against the predicted model P01583: TM-score 0.99, RMSD 0.42 Å
- 5UC6 chain A against the predicted model P01583: TM-score 0.99, RMSD 0.42 Å
- 2L5X chain A against the predicted model P01583: TM-score 0.89, RMSD 2.02 Å
- 2L5X chain A against the predicted model P01583: TM-score 0.89, RMSD 2.02 Å
- 2KKI chain A against the predicted model P01583: TM-score 0.86, RMSD 2.18 Å
- 2KKI chain A against the predicted model P01583: TM-score 0.86, RMSD 2.18 Å
Elsewhere
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