UniProt P01303
Neuropeptide Y (P01303)
Neuropeptide Y (UniProt P01303): 12 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P01303
- Protein
- Neuropeptide Y
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 12 · 4 records with a druggable one
Structures
13 records of P01303 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1QFA | Structure of a neuropeptide Y Y2 agonist | solution nmr | A | — | — |
| 1QFA | Structure of a neuropeptide Y Y2 agonist | solution nmr | A | — | — |
| 1RON | NMR solution structure of human neuropeptide Y | solution nmr | A | — | — |
| 1RON | NMR solution structure of human neuropeptide Y | solution nmr | A | — | — |
| 7RTA | Crystal structures of human pyy and npy | x-ray diffraction | N | NH2 | — |
| 7VGX | Neuropeptide Y Y1 receptor (NPY1R) in complex with G protein and its endogeneous peptide-agonist… | electron microscopy | L | — | — |
| 7X9A | Cryo-EM structure of neuropeptide Y Y1 receptor in complex with npy and gi | electron microscopy | P | — | — |
| 7X9B | Cryo-EM structure of neuropeptide Y Y2 receptor in complex with NPY and Gi | electron microscopy | P | — | 2 (best 0.66) |
| 7X9B | Cryo-EM structure of neuropeptide Y Y2 receptor in complex with npy and gi | electron microscopy | P | — | — |
| 7YOO | Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi | electron microscopy | L | — | 3 (best 0.70) |
| 8K6M | Structural complex of neuropeptide Y receptor 1 | electron microscopy | E | — | 4 (best 0.74) |
| 8K6N | Structural complex of neuropeptide Y receptor 2 | electron microscopy | D | — | 3 (best 0.74) |
| P01303 | AlphaFold monomer V2.0 prediction for pro-neuropeptide Y (P01303) | predicted | A | — | — |
Ligands
- NH2 · Amino group · in 1 record
Experiment against prediction
- 7X9A chain P against the predicted model P01303: TM-score 0.76, RMSD 1.83 Å
- 7RTA chain N against the predicted model P01303: TM-score 0.72, RMSD 1.56 Å
- 7X9B chain P against the predicted model P01303: TM-score 0.68, RMSD 1.66 Å
- 7X9B chain P against the predicted model P01303: TM-score 0.68, RMSD 1.66 Å
- 8K6N chain D against the predicted model P01303: TM-score 0.65, RMSD 1.28 Å
- 7VGX chain L against the predicted model P01303: TM-score 0.55, RMSD 1.23 Å
- 7YOO chain L against the predicted model P01303: TM-score 0.55, RMSD 1.39 Å
- 8K6M chain E against the predicted model P01303: TM-score 0.51, RMSD 2.45 Å
- 1QFA chain A against the predicted model P01303: TM-score 0.46, RMSD 0.99 Å
- 1QFA chain A against the predicted model P01303: TM-score 0.46, RMSD 0.99 Å
Elsewhere
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