UniProt P01258

Calcitonin (P01258)

Calcitonin (UniProt P01258): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: P01258
Protein: Calcitonin
Experimental structures: 6
Predicted models: 1
Ligands: 1
Pockets: 3 · 2 records with a druggable one

Structures

7 records of P01258 in the MolNFT archive: 6 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
2JXZ	Solution Conformation of A Non-Amyloidogenic Analogue of Human Calcitonin in Sodium Dodecyl Sulfate…	solution nmr	A	—	—
2JXZ	Solution conformation of a non-amyloidogenic analogue of human calcitonin in sodium dodecyl sulfate…	solution nmr	A	—	—
7TYH	Human Amylin2 Receptor in complex with Gs and human calcitonin peptide	electron microscopy	P	—	2 (best 0.75)
7TYH	Human AMYLIN2 receptor in complex with gs and human calcitonin peptide	electron microscopy	P	NH2	—
7TYO	Calcitonin receptor in complex with Gs and human calcitonin peptide	electron microscopy	P	—	1 (best 0.74)
7TYO	Calcitonin receptor in complex with gs and human calcitonin peptide	electron microscopy	P	NH2	—
P01258	AlphaFold monomer V2.0 prediction for calcitonin (P01258)	predicted	A	—	—

Ligands

NH2 · Amino group · in 2 records

Experiment against prediction

2JXZ chain A against the predicted model P01258: TM-score 0.62, RMSD 1.08 Å
2JXZ chain A against the predicted model P01258: TM-score 0.62, RMSD 1.08 Å
7TYH chain P against the predicted model P01258: TM-score 0.48, RMSD 2.09 Å
7TYH chain P against the predicted model P01258: TM-score 0.48, RMSD 2.09 Å
7TYO chain P against the predicted model P01258: TM-score 0.43, RMSD 2.49 Å
7TYO chain P against the predicted model P01258: TM-score 0.43, RMSD 2.49 Å

Elsewhere

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