UniProt P01215
Glycoprotein hormones alpha chain (P01215)
Glycoprotein hormones alpha chain (UniProt P01215): 27 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P01215
- Protein
- Glycoprotein hormones alpha chain
- Experimental structures
- 27
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 20 · 5 records with a druggable one
Structures
28 records of P01215 in the MolNFT archive: 27 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1DZ7 | Solution structure of the a-subunit of human chorionic gonadotropin [modeled without carbohydrate… | solution nmr | A | — | — |
| 1DZ7 | Solution structure of the a-subunit of human chorionic gonadotropin [modeled without carbohydrate… | solution nmr | A | — | — |
| 1E9J | Solution structure of the a-subunit of human chorionic gonadotropin [including a single glcnac… | solution nmr | A | — | — |
| 1E9J | Solution structure of the a-subunit of human chorionic gonadotropin [including a single glcnac… | solution nmr | A | — | — |
| 1FL7 | Human follicle stimulating hormone | x-ray diffraction | A, C | — | — |
| 1FL7 | Human follicle stimulating hormone | x-ray diffraction | A, C | — | — |
| 1HCN | Structure of human chorionic gonadotropin at 2.6 ångströms resolution from mad analysis of the… | x-ray diffraction | A | — | — |
| 1HCN | Structure of human chorionic gonadotropin at 2.6 ångströms resolution from mad analysis of the… | x-ray diffraction | A | — | — |
| 1HD4 | Solution structure of the a-subunit of human chorionic gonadotropin [modeled with diantennary… | solution nmr | A | — | — |
| 1HD4 | Solution structure of the a-subunit of human chorionic gonadotropin [modeled with diantennary… | solution nmr | A | — | — |
| 1HRP | Crystal structure of human chorionic gonadotropin | x-ray diffraction | A | — | — |
| 1HRP | Crystal structure of human chorionic gonadotropin | x-ray diffraction | A | — | — |
| 1QFW | Ternary complex of human chorionic gonadotropin with fv anti alpha subunit and fv anti beta subunit | x-ray diffraction | A | — | — |
| 1QFW | Ternary complex of human chorionic gonadotropin with fv anti alpha subunit and fv anti beta subunit | x-ray diffraction | A | — | — |
| 1XWD | Crystal Structure of Human Follicle Stimulating Hormone Complexed with its Receptor | x-ray diffraction | A, D | — | — |
| 1XWD | Crystal structure of human follicle stimulating hormone complexed with its receptor | x-ray diffraction | A, D | — | — |
| 7FIG | luteinizing hormone/choriogonadotropin receptor(S277I)-chorionic gonadotropin-Gs complex | electron microscopy | X | NAG | 3 (best 0.66) |
| 7FIG | Luteinizing HORMONE/CHORIOGONADOTROPIN RECEPTOR(S277I)-chorionic gonadotropin-gs complex | electron microscopy | X | NAG | — |
| 7FIH | luteinizing hormone/choriogonadotropin receptor(S277I)-chorionic gonadotropin-Gs-Org43553 complex | electron microscopy | X | — | 8 (best 0.74) |
| 7FIH | Luteinizing HORMONE/CHORIOGONADOTROPIN RECEPTOR(S277I)-chorionic gonadotropin-gs-ORG43553 complex | electron microscopy | X | — | — |
| 7FII | luteinizing hormone/choriogonadotropin receptor-chorionic gonadotropin-Gs complex | electron microscopy | X | — | 2 (best 0.81) |
| 7FII | Luteinizing HORMONE/CHORIOGONADOTROPIN receptor-chorionic gonadotropin-gs complex | electron microscopy | X | — | — |
| 7T9I | Native human TSH bound to human Thyrotropin receptor in complex with miniGs399 (composite structure) | electron microscopy | A | NAG | 4 (best 0.79) |
| 7T9I | Native human tsh bound to human thyrotropin receptor in complex with MINIGS399 (composite structure) | electron microscopy | A | NAG | — |
| 7UTZ | Human thyrotropin analog TR1402 bound to human thyrotropin receptor in complex with MINIGS399… | electron microscopy | A | NAG | — |
| 7XW5 | TSHR-thyroid stimulating hormone-Gs-ML109 complex | electron microscopy | X | NAG | 3 (best 0.70) |
| 7XW5 | Tshr-thyroid stimulating hormone-gs-ML109 complex | electron microscopy | X | NAG | — |
| P01215 | AlphaFold monomer V2.0 prediction for glycoprotein hormones alpha chain (P01215) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 7 records
Experiment against prediction
- 1XWD chain D against the predicted model P01215: TM-score 0.96, RMSD 0.69 Å
- 1XWD chain D against the predicted model P01215: TM-score 0.96, RMSD 0.69 Å
- 7UTZ chain A against the predicted model P01215: TM-score 0.96, RMSD 0.70 Å
- 7FIG chain X against the predicted model P01215: TM-score 0.95, RMSD 0.76 Å
- 7FIG chain X against the predicted model P01215: TM-score 0.95, RMSD 0.76 Å
- 1XWD chain A against the predicted model P01215: TM-score 0.95, RMSD 0.92 Å
- 1XWD chain A against the predicted model P01215: TM-score 0.95, RMSD 0.92 Å
- 1HCN chain A against the predicted model P01215: TM-score 0.94, RMSD 0.97 Å
- 1HCN chain A against the predicted model P01215: TM-score 0.94, RMSD 0.97 Å
- 7FIH chain X against the predicted model P01215: TM-score 0.94, RMSD 0.91 Å
Elsewhere
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