UniProt P01139
Beta-nerve growth factor (P01139)
Beta-nerve growth factor (UniProt P01139): 16 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P01139
- Protein
- Beta-nerve growth factor
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 10 · 2 records with a druggable one
Structures
17 records of P01139 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BET | New protein fold revealed by a 2.3 ångström resolution crystal structure of nerve growth factor | x-ray diffraction | A | — | — |
| 1BET | New protein fold revealed by a 2.3 ångström resolution crystal structure of nerve growth factor | x-ray diffraction | A | — | — |
| 1BTG | Crystal structure of beta nerve growth factor at 2.5 a resolution in C2 space group with zn ions… | x-ray diffraction | A, B, C | — | — |
| 1BTG | Crystal structure of beta nerve growth factor at 2.5 a resolution in C2 space group with zn ions… | x-ray diffraction | A, B, C | — | — |
| 1SGF | Crystal structure of 7S ngf: a complex of nerve growth factor with four binding proteins (serine… | x-ray diffraction | B, Y | — | — |
| 1SGF | Crystal structure of 7S ngf: a complex of nerve growth factor with four binding proteins (serine… | x-ray diffraction | B, Y | — | — |
| 3IJ2 | Ligand-receptor structure | x-ray diffraction | A, B | — | — |
| 3IJ2 | Ligand-receptor structure | x-ray diffraction | A, B | — | — |
| 4EAX | Mouse NGF in complex with Lyso-PS | x-ray diffraction | A, B, C, D | — | — |
| 4EAX | Mouse ngf in complex with lyso-ps | x-ray diffraction | A, B, C, D | — | — |
| 4XPJ | Crystal structure of Nerve growth factor in complex with lysophosphatidylinositol | x-ray diffraction | A, B | LPY | 3 (best 0.61) |
| 4XPJ | Crystal structure of nerve growth factor in complex with lysophosphatidylinositol | x-ray diffraction | A, B | — | — |
| 5LSD | recombinant mouse Nerve Growth Factor | solution nmr | A, B | — | — |
| 5LSD | Recombinant mouse nerve growth factor | solution nmr | A, B | — | — |
| 6FFY | Structure of the mouse SorCS2-NGF complex | x-ray diffraction | B, C | NAG | 7 (best 0.79) |
| 6FFY | Structure of the mouse SORCS2-ngf complex | x-ray diffraction | B, C | — | — |
| P01139 | AlphaFold monomer V2.0 prediction for beta-nerve growth factor (P01139) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4XPJ chain A against the predicted model P01139: TM-score 0.94, RMSD 1.16 Å
- 4XPJ chain A against the predicted model P01139: TM-score 0.94, RMSD 1.16 Å
- 1BET chain A against the predicted model P01139: TM-score 0.94, RMSD 1.07 Å
- 1BET chain A against the predicted model P01139: TM-score 0.94, RMSD 1.07 Å
- 1SGF chain B against the predicted model P01139: TM-score 0.94, RMSD 1.03 Å
- 1SGF chain B against the predicted model P01139: TM-score 0.94, RMSD 1.03 Å
- 4EAX chain A against the predicted model P01139: TM-score 0.94, RMSD 1.23 Å
- 4EAX chain A against the predicted model P01139: TM-score 0.94, RMSD 1.23 Å
- 1BTG chain B against the predicted model P01139: TM-score 0.94, RMSD 1.22 Å
- 1BTG chain B against the predicted model P01139: TM-score 0.94, RMSD 1.22 Å
Elsewhere
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