UniProt P01127
Platelet-derived growth factor subunit B (P01127)
Platelet-derived growth factor subunit B (UniProt P01127): 10 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P01127
- Protein
- Platelet-derived growth factor subunit B
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
11 records of P01127 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PDG | Crystal structure of human platelet-derived growth factor bb | x-ray diffraction | A, B, C | — | — |
| 1PDG | Crystal structure of human platelet-derived growth factor bb | x-ray diffraction | A, B, C | — | — |
| 3MJG | The structure of a platelet derived growth factor receptor complex | x-ray diffraction | A, B | — | — |
| 3MJG | The structure of a platelet derived growth factor receptor complex | x-ray diffraction | A, B | — | — |
| 4HQU | Crystal structure of human PDGF-BB in complex with a modified nucleotide aptamer (SOMAmer SL5) | x-ray diffraction | A | — | — |
| 4HQU | Crystal structure of human PDGF-bb in complex with a modified nucleotide aptamer (somamer SL5) | x-ray diffraction | A | — | — |
| 4HQX | CRYSTAL STRUCTURE OF HUMAN PDGF-BB IN COMPLEX WITH A Modified nucleotide aptamer (SOMAmer SL4) | x-ray diffraction | A | — | — |
| 4HQX | Crystal structure of human PDGF-bb in complex with a modified nucleotide aptamer (somamer SL4) | x-ray diffraction | A | — | — |
| 4QCI | PDGF-B blocking antibody bound to PDGF-BB | x-ray diffraction | C, D | — | — |
| 4QCI | PDGF-B blocking antibody bound to PDGF-bb | x-ray diffraction | C, D | — | — |
| P01127 | AlphaFold monomer V2.0 prediction for platelet-derived growth factor subunit B (P01127) | predicted | A | — | 1 (best 0.34) |
Experiment against prediction
- 3MJG chain A against the predicted model P01127: TM-score 0.95, RMSD 0.97 Å
- 3MJG chain A against the predicted model P01127: TM-score 0.95, RMSD 0.97 Å
- 1PDG chain C against the predicted model P01127: TM-score 0.95, RMSD 0.84 Å
- 1PDG chain C against the predicted model P01127: TM-score 0.95, RMSD 0.84 Å
- 1PDG chain A against the predicted model P01127: TM-score 0.95, RMSD 0.98 Å
- 1PDG chain A against the predicted model P01127: TM-score 0.95, RMSD 0.98 Å
- 4HQU chain A against the predicted model P01127: TM-score 0.94, RMSD 0.94 Å
- 4HQU chain A against the predicted model P01127: TM-score 0.94, RMSD 0.94 Å
- 4HQX chain A against the predicted model P01127: TM-score 0.94, RMSD 0.97 Å
- 4HQX chain A against the predicted model P01127: TM-score 0.94, RMSD 0.97 Å
Elsewhere
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